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Vaccine News & Notes — February 2025
Find resources about how vaccine recommendations are made and the promise of mRNA technology beyond vaccines. Also, get 3 tips and additional resources to help with fact checking.
Research Q-and-A with Juan D. Matute, MD, Attending Neonatologist
In July 2024, Juan D. Matute, MD, joined our team as an attending neonatologist in the Harriet and Ronald Lassin Newborn/Infant Intensive Care Unit (N/IICU) at Children’s Hospital of Philadelphia.
Children’s Hospital of Philadelphia Researchers Show How Patellar Instability Affects Knee Development in Growing Youth
Researchers at Children’s Hospital of Philadelphia (CHOP) demonstrated how trochlear anatomy evolves during pediatric development with and without recurrent patellofemoral instability (PFI), a condition where the kneecap repeatedly slips out of its groove, causing pain, swelling and difficulty with physical activity. The findings, recently reported in a landmark study in the American Journal of Sports Medicine, highlighted that PFI in growing children worsens trochlear dysplasia, which can result in further kneecap instability, while those without PFI experienced natural improvements.
Children’s Hospital of Philadelphia Researchers Lead First Study to Identify Molecular Basis of Food Allergy
In a landmark translational study, collaborators identified the specific milk protein that triggered a patient’s case of eosinophilic esophagitis
Rite Aid Healthy Futures Awards Children’s Hospital of Philadelphia’s Healthier Together Program $200,000 Grant to Expand Access
Children’s Hospital of Philadelphia’s Healthier Together program has received a $200,000 grant from Rite Aid Healthy Futures to expand access to healthy meals at daycares in West and Southwest Philadelphia.
Type 1 Diabetes Prevention Program at CHOP
Tzield, the first FDA-approved treatment to delay the onset of clinical diabetes, is now available in the Type 1 Diabetes clinic at CHOP
The Critical Role of Accurate Testing in Identifying Children with Focal Hyperinsulinism
Learn more about how genetic testing offers the best means of distinguishing between the focal and diffuse forms of HI in children.
DISCOVERY of Risk Factors for Type 2 Diabetes in Youth
CHOP is recruiting research participants for a new observational study called, “DISCOVERY of Risk Factors for Type 2 Diabetes in Youth,” led by Lorraine L. Katz, MD.

Researchers at Children’s Hospital of Philadelphia Find Heart Transplant Waitlist Allocation Changes and Advancements in Clinical Care Improved Patient Outcomes for Some but Not All
Heart transplant policies underwent significant changes in 2016 and 2018, altering how hearts are allocated to patients waiting for a transplant. These changes aimed to improve survival rates and outcomes for patients on the transplant waitlist by prioritizing those with the most pressing needs. In a recent study in Circulation, researchers at Children’s Hospital of Philadelphia (CHOP) reviewed the outcomes and found some patient groups benefitted from the allocation updates, while others did not experience the same level of improvement.
CHOP hosts Global Advances in Celiac Disease conference
CHOP’s Celiac Center hosted the Beyond Celiac Research Summit recently, detailing the latest celiac research and best practices in long-term treatment