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Children’s Hospital of Philadelphia Preclinical Study Unveils Promising New Treatment Approach for Fanconi Anemia Patients
In a preclinical study, researchers at Children’s Hospital of Philadelphia (CHOP) demonstrated a novel treatment strategy for patients with Fanconi anemia (FA), a rare genetic disease resulting in loss of blood-forming stem cells in the bone marrow. The researchers successfully used in situ mRNA delivered directly into the body by lipid nanoparticles (LNPs) to target bone marrow cells and transiently restore stem cell function in patients with FA.
Children’s Hospital of Philadelphia Experts Unveil Innovative Fetal Medicine Data Platform
An interprofessional team at Children’s Hospital of Philadelphia is transforming CHOP’s approach to fetal medicine through a first-of-its-kind data integration platform. The Clinical Outcomes Data Archive (CODA) platform offers clinicians real-time data to help inform earlier interventions and treatment strategies in CHOP’s Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment (CFDT). A paper outlining CODA’s benefits, applications and potential broader impact was recently published in the journal Fetal Diagnosis and Therapy.
Children’s Hospital of Philadelphia Researchers Identify Important Role of Mitochondria in Immune Response to Cancer
Preclinical study suggests immunotherapies targeting mitochondria could treat certain tumors.
Reflections on a CHOP Global Health Allies Work Week in the Dominican Republic
Aimee Ortega describes her thoughts participating in the Global Health Allies Program in the Dominican Republic.
On the Bookshelf: Understanding and Addressing Misinformation About Science
Find out about the topics discussed in a comprehensive analysis of misinformation in science published by the National Academies of Science.
Technically Speaking: Provider Vaccination Prompts During Patient Visits
Find out about different types of provider prompts to increase vaccination rates, and see some reasons to consider designing prompts for your practice.
In the Journals: Recombinant or Standard-dose Influenza Vaccine for Adults Under 65?
Read about the results of a research study comparing recombinant influenza vaccine with standard-dose influenza vaccine in adults less than 65 years of age.
Vaccine Resources: Abstract Submission Opportunity, Trainings, and Vaccine Administration Tools
Check out several resources that may be helpful for your vaccine-related efforts, including abstract submission opportunity, infodemic management courses, updated vaccine administration resources, and more.
News & Views: Vaccine Tips and Tricks from Your Colleagues
Find invaluable vaccination tips shared during the VEC team’s interactions with healthcare providers at local and national conferences.
Children’s Hospital of Philadelphia Researchers Advance Best Practices, Guidelines, and Care Path Objectives for Early-Onset Sepsis
Researchers at Children’s Hospital of Philadelphia (CHOP) recently reviewed best practices, guidelines, and care path objectives for early-onset sepsis (EOS), an invasive bacterial or fungal infection that occurs in infants within the first week of life and can be fatal. Their recommendations were recently published in Clinics in Perinatology.