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Children’s Hospital of Philadelphia Researchers Find Promising Preclinical Results for High-Risk Neuroblastoma
Researchers at Children’s Hospital of Philadelphia (CHOP) demonstrated a promising new approach in the fight against high-risk neuroblastoma, a common and potentially deadly childhood cancer that can occur within the peripheral nervous system. The study, recently published in Nature Communications, found that chimeric antigen receptor (CAR) T-cell therapy targeting two markers on neuroblastoma cancer cells simultaneously boosted overall immune response by engaging adaptive and innate immunity in preclinical models.
Researchers at Children’s Hospital of Philadelphia Advocate for Energy Drink Regulation
Energy drinks, marketed for boosting energy, concentration, and athletic performance, can pose significant cardiovascular risks, including death. Despite the American Academy of Pediatrics’ advice against caffeine consumption by children and adolescents, the United States remains the least regulated country and should take immediate steps to protect vulnerable populations, leading cardiology researchers at Children’s Hospital of Philadelphia (CHOP) urged in a recent commentary in the Journal of Pediatrics.
Children's Hospital of Philadelphia Clinicians Awarded with Hyundai Hope On Wheels Grants Totaling $650,000 to Fuel Pediatric Cancer Research
Dr. Adam Wolpaw and Dr. Timothy Spear of Children's Hospital of Philadelphia (CHOP) received the Scholar Hope Award and Young Investigator Award respectively from Hyundai Hope On Wheels.
Children’s Hospital of Philadelphia Researchers Report Encouraging First Evidence of Effective New Gene Therapy to Treat Multiple Sulfatase Deficiency
The ex vivo gene therapy improved sulfatase production and reduced symptoms associated with the disease in preclinical models
Back to school: Director of CHOP’s Sleep Center offers tips on getting children back on a sleep schedule
Dr. Christopher Cielo, Director of CHOP’s Sleep Center, was featured on Fox29 Philadelphia offering tips on getting children back on a sleep schedule for the new school year.
Children’s Hospital of Philadelphia Researchers Develop Zebrafish Model for Studying Rare Metabolic Disease
Preclinical model has already revealed two drugs that could be repurposed for treatment.
News & Views — RSV Prevention in Children: A Year in Review
See what we’ve learned about the effectiveness and safety of RSV prevention for children after the first season of having these new tools.
In the Journals: Does Shingles Vaccination Prevent Dementia?
Check out the findings of a recent study that examined the connection between shingles vaccine and dementia.
On the Bookshelf — Red Book: 2024 Report of the Committee on Infectious Diseases, 33rd Edition
Find a summary of recent updates to the Red Book, a valuable resource for healthcare providers.
Technically Speaking: 6 Tips for Sustaining Change in QI Efforts
Get 6 tips for sustaining QI efforts.