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Children’s Hospital of Philadelphia Researchers Use a “Trojan Horse” Approach to Develop New Antimalarial Drugs
Understanding how the parasites operate gives important insight into drug development for needed novel therapies
Solution for Rare and Complex Early-Onset Kidney Stones
This clinical case study describes a patient with early onset cystinuria, a rare genetic cause of kidney stones, that was first managed by multiple unsuccessful procedures and surgeries before referral to Children’s Hospital of Philadelphia.
Feature Article: 4 Vaccine Considerations for Those with Chronic Medical Conditions, Including Disabilities
Find four considerations that can help those who have chronic or disabling medical conditions navigate vaccine decisions.
Vaccine News & Notes — March 2025
Find info about the latest cases of measles and a video by Dr. Paul Offit providing a generational perspective on vaccines.
"Just the Vax" Trivia Corner
In Africa, many families didn’t name their children until the threat of what vaccine-preventable disease passed? Find out.
Improving Hypospadias Care Delivery through a CORES Research Grant
Christopher J. Long, MD, and his team utilized a Center for Outcomes Research in Surgery (CORES) grant to make considerable improvements to hypospadias care at CHOP.
Insights from the Gut Cell Atlas Convening 2024
The 2024 Gut Cell Atlas (GCA) Convening highlighted the most recent research advances into understanding the biology of Crohn’s disease. Drs. Kate Hamilton and Tatiana Karakasheva represent the Children’s Hospital of Philadelphia Research Institute in this initiative, which aims to build a detailed catalog the cell types composing human small and large intestines, further our understanding of Crohn's disease, and identify pathways towards curative therapy and ultimately, prevention.
2024 Research Annual Report, Did You Know: With Kathryn Hamilton, PhD, and Amanda Muir, MD
Doctors Amanda Muir and Kate Hamilton share a common interest in using patient-derived organoids to study pediatric gastrointestinal (GI) diseases. In 2019, they established the Gastrointestinal Epithelium Modeling Program, a collaborative effort dedicated to accelerating discovery and innovation in the search for cures and prevention strategies for these diseases.
March 2025: Vaccines and Infectious Diseases in the News
Dr. Paul Offit talks about the current measles outbreak in western Texas and recounts other measles outbreaks, including one in Philadelphia in 1991 when he was on the frontlines caring for affected children.
Children’s Hospital of Philadelphia Raises More Than $745,000 for Rare Disease Research at Cheers for CHOP
On Saturday, February 22, 2025, Children's Hospital of Philadelphia (CHOP) hosted Cheers for CHOP, presented by Calvin Schmidt and family, at The Fillmore. The event benefitted rare disease research at CHOP, where rare cases are not so uncommon. Every dollar of the $745,000 (and counting!) raised will help our teams continue their work of translating rare disease research into more precise and personalized care for patients with some of the most complex medical cases.