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Type 1 Diabetes Prevention Program at CHOP
Tzield, the first FDA-approved treatment to delay the onset of clinical diabetes, is now available in the Type 1 Diabetes clinic at CHOP
DISCOVERY of Risk Factors for Type 2 Diabetes in Youth
CHOP is recruiting research participants for a new observational study called, “DISCOVERY of Risk Factors for Type 2 Diabetes in Youth,” led by Lorraine L. Katz, MD.

Researchers at Children’s Hospital of Philadelphia Find Heart Transplant Waitlist Allocation Changes and Advancements in Clinical Care Improved Patient Outcomes for Some but Not All
Heart transplant policies underwent significant changes in 2016 and 2018, altering how hearts are allocated to patients waiting for a transplant. These changes aimed to improve survival rates and outcomes for patients on the transplant waitlist by prioritizing those with the most pressing needs. In a recent study in Circulation, researchers at Children’s Hospital of Philadelphia (CHOP) reviewed the outcomes and found some patient groups benefitted from the allocation updates, while others did not experience the same level of improvement.
CHOP hosts Global Advances in Celiac Disease conference
CHOP’s Celiac Center hosted the Beyond Celiac Research Summit recently, detailing the latest celiac research and best practices in long-term treatment
Children’s Hospital of Philadelphia Preclinical Study Unveils Promising New Treatment Approach for Fanconi Anemia Patients
In a preclinical study, researchers at Children’s Hospital of Philadelphia (CHOP) demonstrated a novel treatment strategy for patients with Fanconi anemia (FA), a rare genetic disease resulting in loss of blood-forming stem cells in the bone marrow. The researchers successfully used in situ mRNA delivered directly into the body by lipid nanoparticles (LNPs) to target bone marrow cells and transiently restore stem cell function in patients with FA.

Children’s Hospital of Philadelphia Experts Unveil Innovative Fetal Medicine Data Platform
An interprofessional team at Children’s Hospital of Philadelphia is transforming CHOP’s approach to fetal medicine through a first-of-its-kind data integration platform. The Clinical Outcomes Data Archive (CODA) platform offers clinicians real-time data to help inform earlier interventions and treatment strategies in CHOP’s Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment (CFDT). A paper outlining CODA’s benefits, applications and potential broader impact was recently published in the journal Fetal Diagnosis and Therapy.
Children’s Hospital of Philadelphia Researchers Identify Important Role of Mitochondria in Immune Response to Cancer
Preclinical study suggests immunotherapies targeting mitochondria could treat certain tumors.
Reflections on a CHOP Global Health Allies Work Week in the Dominican Republic
Aimee Ortega describes her thoughts participating in the Global Health Allies Program in the Dominican Republic.
On the Bookshelf: Understanding and Addressing Misinformation About Science
Find out about the topics discussed in a comprehensive analysis of misinformation in science published by the National Academies of Science.
Technically Speaking: Provider Vaccination Prompts During Patient Visits
Find out about different types of provider prompts to increase vaccination rates, and see some reasons to consider designing prompts for your practice.