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Children’s Hospital of Philadelphia Researchers Boost Widespread Use of Dental Varnish Across Pediatric Network
Researchers demonstrated how a multifaceted intervention approach significantly improved the rate of dental varnish applications to help strengthen tooth enamel and prevent decay. The results exceeded the goal for the study, and improvements were consistent across insurance plans, race and ethnicity, providing an important framework for keeping teeth healthy.
Promising New Preclinical Therapy Offers Hope in the Development of Precision Medicine Treatments for Aggressive Cancers
CHOP researchers developed CDX0239-PBD, a novel antibody-drug conjugate that demonstrates exceptional effectiveness against cancers expressing the ALK protein, achieving durable tumor responses in preclinical models. This breakthrough could pave the way for new precision medicine treatments, enhancing patient outcomes and reducing the side effects associated with existing therapies.
"Just the Vax" Trivia Corner
What virus can occur in both humans and chimpanzees? Find out.
Feature Article: New Video and Podcast Series — Get Info and a Sneak Peek
Get vaccine info while on the go with “VEC Vaccine Notes.” This new series will offer information from our webpages in video and podcast formats.
Vaccine News & Notes — September 2025
Find recent data on vaccine coverage among teens, resources on how to assess the quality of scientific info, and a new tool that evaluates the effects of cuts to NIH grants on U.S. counties.
Automated Smoking Interventions Offered to Parents through Pediatric Primary Care May Curb Their Tobacco Habits
Researchers from Children’s Hospital of Philadelphia (CHOP) and Mass General Brigham found that integrating an automated smoking cessation intervention for parents into pediatric primary care demonstrated increased treatment received and reduced cigarettes smoked.
First-of-its-Kind Initiative to Provide Custom-Designed, Medically Safe Backpacks to Cancer Patients
A new program within the Cancer Center at Children’s Hospital of Philadelphia (CHOP) will support caregivers to safely and comfortably manage their child’s leukemia. It’s called Backpacks With Barbara, a first-of-its-kind initiative that will provide 300 custom-designed, kid-friendly and medically safe backpacks to patients at CHOP undergoing blinatumomab therapy, a cutting-edge immunotherapy used to treat B-cell acute lymphoblastic leukemia.

Preventing Kidney Stones
Kidney stones have become more common among children and young adults over the past few decades. Get expert advice that everyone can follow to prevent kidney stones.
A better surgical option when separating fingers fused by soft tissue
CHOP research demonstrates that a skin graftless technique has a much lower complication rate.
Why newborns need the vitamin K shot at birth
This one injection helps prevent strokes and internal bleeding — yet more parents are saying no. Here's what every new family should know.