Mudit Gupta, MD, PhD
About Mudit Gupta, MD, PhD
Titles
Cardiac Fellow
Assistant Professor, Perelman School of Medicine at the University of Pennsylvania
Certifications
Pediatrics – American Board of Pediatrics
Pediatric Cardiology – American Board of Pediatrics
Awards and Honors
2015, George W. Householder, III Memorial Prize, University of Pennsylvania
2008, Regents Award, University of Michigan
2007-2008, James B. Angell Scholar, University of Michigan
Leadership and Memberships
2021-present, Society of Cardiovascular Angiography and Interventions,
2021-present, American Academy of Pediatrics
2019-present, American Heart Association
Editorial and Academic Positions
Editorial positions
2024-present, 3D Printing In Medicine, Reviewer
2021-present, International Journal of Cardiovascular Imaging, Reviewer
Education & training
Graduate Degree
PhD in Cell and Molecular Biology - Perelman School of Medicine University of Philadelphia, Philadelphia, PA
Medical Degree
MD - Perelman School of Medicine University of Philadelphia, Philadelphia, PA
Residency
Pediatrics - Children's Hospital of Philadelphia, Philadelphia, PA
Fellowship
Pediatric Cardiology - Children's Hospital of Philadelphia, Philadelphia, PA
Pediatric Congenital Interventional Cardiology - Children's Hospital of Philadelphia, Philadelphia, PA
Publications
Publications
2024
Corren, Y.B., Gupta, M., Tang, J., Smith, C.L., Callahan, R., Dori, Y., Rome, J.J., Gillespie, M.J., O’Byrne, M.L. From Text to Data: Automatically Extracting Data from Catheterization Reports Using Generative AI. J Soc Cardio Angio Interv. 2024.
Gupta, M., Corren, Y.B, Gillespie, M.J., Leeth, E.B., Callahan, R. Iatrogenic Aortopulmonary Communication Following Intentional Pulmonary Bioprosthetic Valve Fracture. JACC: Cardiovascular Interventions. 2024.
Gartenberg, A.J., O’Byrne, M.L., Leeth, E.B., Tang, J., Gupta, M., Rome, J.J., Callahan, R. Pulmonary Artery Wedge Pressure Can Underestimate Direct Pulmonary Vein Pressure in Pediatric Pulmonary Vein Stenosis. J Soc Cardio Angio Interv. 2024.
2023
Jolley, M.A., Sulentic, A., Amin, S., Gupta, M., Ching, S., Cianciulli, A., Wang, Y., Sabin, P., Zelonis, C., Daemer, M., Silvestro, E., Coleman, K., Ford, L.K., Edelson, J.B., Ruckdeschel, E.S., Cohen, M.S., Nicolson, S.C., Gillespie, M.J. Introduction of Transcatheter Edge-to-Edge Repair in Patients with Congenital Heart Disease at a Children’s Hospital. Catheter Cardiovasc Interv. 2023 Dec 27.
Niccum, M., Gupta, M., Rome, J., O’Byrne, M.L. 2023 Sep. Coil Embolization of a Ruptured Mycotic Coronary Artery Aneurysm in a Pediatric Patient. J Am Coll Cardiol Case Rep, 21, (null).
Sulentic, A., Gupta, M., Amin, S., Wang, Y., Vaiyani, D., Sabin, P., Partington, S.L., Gillespie, M.J., Jolley, M.A. 2023 Sep. 3-Dimensional Modeling Guided Transcatheter Repair of Dehisced Pulmonary Venous Baffle with Gore ASD Device. J Am Coll Cardiol Case Rep, 21, (null).
2017
Poleshko, A.*, Shah, P.P.*, Gupta, M.*, Babu, A., Morley, M.P., Manderfield, L.J., Ifkovits, J.L., Calderon, D., Aghajanian, H., Sierra-Pagán, J.E., Sun, Z., Wang, Q., Li, L., Dubois, N.C., Morrisey, E.E., Lazar, M.A., Smith, C.L., Epstein, J.A., Jain, R. 2017. Genome-nuclear lamina interactions regulate progenitor cell behavior during cardiac development. Cell, 171, 3, 573-587. *These authors contributed equally to this work.
2016
Aghajanian, H., Cho, Y.K., Manderfield, L.J., Herling, M.R., Gupta, M., Ho, V.C., Li, L., Degenhardt, K., Aharonov, A., Tzahor, E., Epstein, J.A. 2016. Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor. Nature Communications, 7, 12038.
2015
Jain, R.*, Li, D.*, Gupta, M., Manderfield, L.J., Ifkovits, J.L., Wang, Q., Liu, F., Liu, Y., Poleshko, A., Padmanabhan, A., Raum, J.C., Li, L., Morrisey, E.E., Lu, M.M., Won, K.J., Epstein, J.A. 2015. HEART DEVELOPMENT. Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts. Science, 348, 6242. *These authors contributed equally to this work.
Jain, R.*, Barkauskas, C.E.*, Takeda, N., Bowie, E.J., Aghajanian, H., Wang, Q., Padmanabhan, A., Manderfield, L.J., Gupta, M., Li, D., Li, L., Hogan, B.L.M., Epstein, J.A. 2015. Plasticity of Hopx+ Type I alveolar cells to regenerate Type II cells in the lung. Nature Communications, 6, 6727.
*These authors contributed equally to this work.
2014
Manderfield, L.J., Engleka, K.A., Aghajanian, H., Gupta, M., Yang, S., Li, L., Baggs, J.E.,Hogenesch, J.B., Olson, E.N., Epstein, J.A. 2014. Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest. Cell Reports, 9, 5, 1885-95.
Aghajanian, H., Choi, C., Ho, V.C., Gupta, M., Singh, M.K., Epstein, J.A. 2014. Semaphorin 3d and semaphorin 3e direct endothelial motility through distinct molecular signaling pathways. Journal of Biological Chemistry, 289, 26, 17971-9.
2013
Singh, N.*, Gupta, M.*, Trivedi, C.M., Singh, M.K., Li, L., Epstein, J. A. 2013. Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression. Developmental Biology, 377, 333–44. *These authors contributed equally to this work.
2011
Shen, C.J., Raghavan, S., Xu, Z., Baranski, J.D., Yu, X., Wozniak, M.A., Miller, J.S., Gupta, M., Buckbinder, L., Chen, C.S. 2011. Decreased cell adhesion promotes angiogenesis in a Pyk2-dependent manner. Experimental Cell Research, 317, 13,1860-71.
Aokye-Danso, F., Trivedi, C.M., Juhr, D., Gupta, M., Cui, Z., Tian, Y., Zhang, Y., Yang, W., Gruber, P.J., Epstein, J.A., Morrisey, E.E. 2011. Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency. Cell Stem Cell, 8, 4, 376-88.
2009
Luker, K.E., Gupta, M., Steele, J.M., Foerster, B.R., Luker, G.D. 2009. Imaging ligand-dependent activation of CXCR7. Neoplasia (New York, N.Y.), 11, 10, 1022-35.
Luker, K., Gupta, M., Luker, G. 2009. Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7. BioTechniques, 47, 1, 625-32.
Song, J.W., Cavnar, S.P., Walker, A.C., Luker, K.E., Gupta, M., Tung, Y.C., Luker, G.D., Takayama, S. 2009. Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells. PloS One, 4, 6, e5756.
Luker, K.E., Gupta, M., Luker, G.D. 2009. Imaging chemokine receptor dimerization with firefly luciferase complementation. FASEB Journal, 23, 3, 823-34.
2008
Luker, K.E., Gupta, M., Luker, G.D. 2008. Imaging CXCR4 signaling with firefly luciferase complementation. Analytical Chemistry, 80, 14, 5565-73.
Abstracts (includes Posters and Scientific Presentations)
2023
Vaiyani, D., Ford, B., Gupta, M., Dietzman, T., Biko, D., DeWitt, A.G., Gillespie, M.J., O’Byrne, M.L., Rome, J.J., Smith, C.L., Dori, Y. Lymphatic Intervention Following Superior Cavo-Pulmonary Anastomosis Potentially Allows for Successful Fontan Completion. American Heart Association Scientific Sessions 2023. Philadelphia, PA, November 10, 2023. Poster Presentation.
Corren, Y.B.,* Gupta. M.,* Sunderland, K., Lasso, A., Cianciulli, A., Amin, S., Williams, T.R., O’Byrne, M.L., Jolley, M.A. CT-based Simulation of Projection Angiography Using the SlicerHeart Virtual Cath Lab. 8th World Congress of Pediatric Cardiology and Cardiac Surgery, Washington DC, August 30, 2023. Poster Presentation. *These authors contributed equally to this work
Gupta, M., Tomasulo, C.E., Ford, B., Srinivasan, A.S., Krishnamurthy, G., Escobar, F.A., Dori, Y., Smith, C.L. Identification and Percutaneous Embolization of Abnormal Hepatopulmonary Lymphatic Connections. SCAI Scientific Sessions 2023. Phoenix, AZ, May 20, 2023. Featured Oral Presentation.
2022
Gupta, M., Vaiyani, D., DeWitt, A.G., Favilla, E., Pinto, E., Biroc, L., Rome, J.J., Smith, C.L., Dori, Y. Percutaneous Treatment of Thoracic Duct Outlet Stenosis for Patients with Disorders of Lymphatic Perfusion. PICS Symposium 2022, Chicago, IL, September 7, 2022. Oral Presentation.
Gupta, M., Cianciulli, A., Pinter, C., Dewey, H., Amin, S., Lasso, A., O’Byrne, M.L., Glatz, A.C., Jolley, M. Development of a 3D Modeling Tool for Procedural Planning of Ductal Stenting. SCAI Scientific Sessions 2022, Atlanta, GA, May 19, 2022. Featured Oral Presentation.
Lectures by Invitation
2023
Gupta, M. CHOP Neonatology Case Review – Invited Content Expert. “Postnatal resuscitation of dTGA”. February 21, 2023
2022
Gupta, M. Paul M. Weinberg Congenital Cardiac Morphology Course. Virtual Reality Specimen Presenter. October 21, 2022.
Gupta, M. Updates in Primary Care CME Seminar, CHOP Care Network. “Cardiac Sports Physicals”. August 3, 2022.
Gupta, M. Updates in Primary Care Conference, Children’s Hospital of Philadelphia. “Cardiac Sports Physicals and Murmurs”. May 14, 2022.
2021
Gupta, M. Cardiac Center Nursing Education. “Lymphatics: The 3rd Circulatory System”. November 1, 2021.
Gupta, M. PICS Symposium 2021 Live Case. Las Vegas, NV. “Transcatheter Harmony Valve Placement”. September 2, 2021.
Editorials, Reviews, Chapters
2023
Gartenberg, A.J.,* Gupta, M.,* Gillespie, M.J., Rome, J.J. (2023) Chapter 91: Hemodynamic Assessment and Transcatheter Therapy for Congenital Heart Disease. 4th Edition. *These authors contributed equally to this work
2016
Jain, R.,* Gupta, M.,* and Epstein, J.A. (2016) Chapter 15: Epigenetics. In Rickert-Sperling, S., Kelly, R.G., Driscoll, D.J., (Eds.) Congenital Heart Diseases: The Broken Heart. (pp. 203-221). Vienna, Austria: Springer-Verlag Wien. *These authors contributed equally to this work