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Research Studies

Trisomy 21 (Down Syndrome) Research Studies

Eligible age

Assent and Decision-Making Study in Down Syndrome

We are inviting teens and young adults with Down Syndrome and their care givers to participate in a study that seeks to improve the way we explain research studies to individuals with Down Syndrome. Our goal is to create tools to help with explaining what it means to be in

a research study and to get feedback on how we can improve these tools.


Phase: N/A

Actively recruiting: Yes

Category: Adults, Children

Conditions: Trisomy 21 (Down Syndrome)

Down Syndrome and Sleep Apnea Study (DOSA)

This research study is being conducted to look at oxygen as a treatment of obstructive sleep apnea (OSA) in children with Down syndrome. The main reason for the study is to show how 6 months of oxygen treatment while sleeping affects the participants sleep, quality of life, breathing, heart and if it makes the participant feel better.

Phase: Phase II

Actively recruiting: Yes

Category: Children

Conditions: Trisomy 21 (Down Syndrome), Obstructive Sleep Apnea

Home Sleep Apnea Testing in Children (HATCh) Study

The purpose of this research is to compare home sleep apnea testing (HSAT) to in-lab overnight sleep study. We want to see if HSAT in children can be an alternative to in-lab sleep study for the diagnosis of obstructive sleep apnea.

Phase: Phase III

Actively recruiting: Yes

Category: Children

Conditions: Trisomy 21 (Down Syndrome), Obstructive Sleep Apnea

Risk and Obesity in Kids and Teens with Down Syndrome Study

Down syndrome can make it easier for kids and teens to become overweight. Teenagers with DS often have more body fat than other people their age and might have higher chances of getting health issues like diabetes and heart problems. This study looked at ways to measure body fat and risk for these health problems in kids and teens with Down syndrome compared to other healthy people. The goal was to help doctors find better ways to check for and stop these health problems in kids and teens with Down syndrome.

Phase: N/A

Actively recruiting: No

Category: Adults, Children, Healthy Controls

Conditions: Trisomy 21 (Down Syndrome)

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