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Idiopathic scoliosis

<p>Idiopathic scoliosis is the most common spinal deformity in the world. Like other forms of scoliosis, idiopathic scoliosis affects the curvature of the spine. The condition usually occurs in adolescents 10 to 18 years of age, and is more likely to progress in girls.</p>

Children’s Hospital of Philadelphia Preclinical Study Unveils Promising New Treatment Approach for Fanconi Anemia Patients

Jan 28, 2025

In a preclinical study, researchers at Children’s Hospital of Philadelphia (CHOP) demonstrated a novel treatment strategy for patients with Fanconi anemia (FA), a rare genetic disease resulting in loss of blood-forming stem cells in the bone marrow. The researchers successfully used in situ mRNA delivered directly into the body by lipid nanoparticles (LNPs) to target bone marrow cells and transiently restore stem cell function in patients with FA.

pregnancy ultrasound

Children’s Hospital of Philadelphia Experts Unveil Innovative Fetal Medicine Data Platform

Jan 27, 2025

An interprofessional team at Children’s Hospital of Philadelphia is transforming CHOP’s approach to fetal medicine through a first-of-its-kind data integration platform. The Clinical Outcomes Data Archive (CODA) platform offers clinicians real-time data to help inform earlier interventions and treatment strategies in CHOP’s Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment (CFDT). A paper outlining CODA’s benefits, applications and potential broader impact was recently published in the journal Fetal Diagnosis and Therapy.

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