CHOP’s “Advancing Craniofacial Treatment with Genomics and Gene Therapy” Frontier Program is poised to harness genomic technologies to spearhead innovations in gene therapy, improve diagnostics, predict treatment outcomes and develop new therapies for children.

Our innovative fetal patient registry and data management system has made remarkable strides impacting both clinical care and research.

Expanded criteria for FETO procedure and transition to exclusively using muscle flap repair.

In its first year, our Newborn/Infant Intensive Care Unit at CHOP’s Middleman Family Pavilion in King of Prussia had over 250 admissions and expanded from 10 beds to 18.

An experimental gene therapy, studied in a preclinical model of Batten disease, was found to slow symptoms and extend lifespan

Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania unlocked important new insights in how the immune system selects the right signals to alert T cells, a vital step in the prevention and treatment of serious illness. The findings were published in the journal Proceedings of the National Academy of Sciences (PNAS).

A report estimates that vaccines were directly responsible for a 40% decrease in infant deaths over the last 50 years. Find out more. You'll also learn about the rates of long COVID and about antibiotic-resistant bacteria in Ukraine.

Watch as Dr. Handy discusses which adults might benefit from an additional dose of polio vaccine.

Unsure where to go to for trusted information about vaccines? Check out our list of resources. You'll also learn about why more information and access means more care when consuming that information.

In this piece, Dr. Adzick reflects on the impact the center he helped establish 30 years ago has had on the field and on families.