The earlier PHACE syndrome is diagnosed, the better the chance to quickly intervene and reduce long-term consequences. A few clues can aid in early detection.

In fetuses with open spinal dysraphism, the risk of talipes is increased with an MMC sac, and a larger sac may result in additional injury through mechanical stretching of the nerves.

Families who receive a diagnosis of the most severe forms of spina bifida need an amazing level of support and care coordination from prenatal diagnosis through delivery, treatment and discharge.

Our goal is to optimize the care for children diagnosed with a brain malformation/insult/injury, maximize neurodevelopment in early infancy and provide a smooth transition into adulthood.

Optimizing care for fetuses with potential neurologic diagnoses starts prenatally with a thorough evaluation and support of parents.

Brain development is one of the most complicated processes that occurs in utero. Our team is working to better understand how low oxygen levels affect brain development.

An inside look at our efforts to optimize and advance fetal neurologic care at Children's Hospital of Philadelphia.

Inspired by the separation of conjoined twins Addy and Lily Altobelli, an anonymous donor will match up to $2 million.

The award from March of Dimes recognizes Dr. Flake’s work, which has advanced the science that underlies our understanding of pregnancy, birth, and prenatal development.

Addison and Lilianna Altobelli spent nearly a year at Children’s Hospital of Philadelphia before being separated on October 13, 2021, and are now home in Chicago.