Advancing Fetal Neurologic Care

At Children’s Hospital of Philadelphia, our goal is to optimize the care and developmental potential for those facing neurologic diagnoses from before birth to young adulthood. The following articles shine a light on these and other efforts by our teams in the Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment and Division of Neurology to advance fetal neurologic care.

• Understanding and Preventing Developmental Hypoxic Brain Injury
• How a Fetal Evaluation Can Help a Fetus with a Potential Neurologic Diagnosis
• Supporting Families Through Prenatal Diagnosis of a Fetal Brain Anomaly
• The Role of the Fetal Spina Bifida APN Program Coordinator
• Recent Study Finds Myelomeningocele Sac Associated with Worse Lower Extremity Neurologic Sequelae
• The Many Faces of PHACE Syndrome
• Comprehensive Prenatal Diagnosis and Care of Agenesis of the Corpus Callosum

Select publications

Pisapia JM, Sinha S, Zarnow DM, Johnson MP, Heuer GG. Fetal ventriculomegaly: Diagnosis, treatment, and future directions. Childs Nerv Syst. 2017;33(7):1113-1123.

Didier RA, Martin-Saavedra JS, Oliver ER, DeBari SE, Bilaniuk LT, Howell LJ, Moldenhauer JS, Adzick NS, Heuer GG, Coleman BG. Fetal intraventricular hemorrhage in open neural tube defects: Prenatal imaging evaluation and perinatal outcomes. AJNR Am J Neuroradiol. 2020;41(10):1923-1929.

Feygin T, Khalek N, Moldenhauer JS. Fetal brain, head, and neck tumors: Prenatal imaging and management. Prenat Diagn. 2020;40(10):1203-1219.

Oliver ER, Heuer GG, Thom EA, Burrows PK, Didier RA, DeBari SE, Martin-Saavedra JS, Moldenhauer JS, Jatres J, Howell LJ, Adzick NS, Coleman BG. Myelomeningocele sac associated with worse lower-extremity neurological sequelae: evidence for prenatal neural stretch injury? Ultrasound Obstet Gynecol. 2020;55(6):740-746.

Moldenhauer JS, Soni S, Jatres J, Gebb J, Khalek N, Paidas Teefey C, Johnson MP, Flake AW, Hedrick HL, Peranteau WH, Heuer GG, Adzick NS. Open fetal surgical outcomes for myelomeningocele closure stratified by maternal body mass index in a large single-center cohort. Fetal Diagn Ther. 2020;47(12):889-893.

Houtrow AJ, MacPherson C, Jackson-Cody J, Rivera M, Flynn L, Burrows PK, Adzick NS, Fletcher J, Gupta N, Howell LJ, Brock JW, Lee H, Walker WO, Thom EA. Prenatal repair and physical functioning among children with myelomeningocele: A secondary analysis of a randomized clinical trial. JAMA Pediatrics. 2021;175(4):e205674.