Skip to main content

Research Studies

Division of Gastroenterology, Hepatology and Nutrition Research Studies

Find research studies available to children cared for by the Division of Gastroenterology, Hepatology and Nutrition team.

Appointments and referrals
Questions or for more information

Recruitment Status

Eligible age

Clinical trial phase

Diet and Motility in IBS

This study seeks to characterize dietary intake in children with IBS and explore severity of symptoms and quality of life. This study uses the G-Tech wireless patch system to define patterns of gut motility in patients with IBS and associate these patterns with dietary intake and GI symptoms. Participants will wear the patches for 7 days as a part of the study. They can be worn under clothing and participants can continue daily activities other than swimming, bathing (although they can shower), and exercising. Stool and urine samples will also be collected to explore the gut microbiome and its association with IBS symptoms, diet, and patterns of gut motility.

We are looking to partner with patients with a confirmed diagnosis of IBS between 8 and 18 years of age who are undergoing dietary modifications such as a low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet.

Phase: Pilot

Actively recruiting: Yes

Category: Adults, Children, One-Time Visit Studies

HEALTHY BITES

Teens ages 14-17 with BMI in the 85th percentile or above and without diabetes are invited to participate in the HEALTHY BITES Research Study. The purpose of this research study is to find out if we can develop a mobile health approach that can improve diet quality in teens.

Phase: Pilot

Actively recruiting: Yes

Category: Children, One-Time Visit Studies, Remote (Online / Phone Call Only) Studies

Pediatric IBD Fatigue Index, and the Pediatric IBD Disability Index Study

Kids with IBD (inflammatory bowel disease) often struggle with tiredness and difficulty doing everyday activities, which can make life harder, but there aren't good tools to measure these problems in children. This study aims to create special tools to measure fatigue and disability in kids aged 2-18. Researchers will talk to kids and their parents to find out what issues matter most and use this information, along with medical records, to design the tools. The goal is to help doctors track these problems better and improve care for children with IBD. This study is being done in collaboration with the Shaare Zedek Medical Center. Participants will be compensated for their time and effort, upon completion of the interview.

Phase: Phase I

Actively recruiting: Yes

Category: Adults, Children, One-Time Visit Studies, Remote (Online / Phone Call Only) Studies

Pediatric Study of Acute Recurrent and Chronic Pancreatitis

The goals of this research study are to learn more about acute recurrent and chronic pancreatitis in order to better understand the disease in the hopes of enhancing future treatment options. If you and your child agree to participate you will each be asked to: meet with the study team at your annual check-up, complete questionnaires about medical history, family history, and quality of life, agree to a one-time blood or saliva sample collection. All participants will be compensated for their time and effort. If you would be interested in participating, please contact study coordinator Lucia Sanchez by phone at 267-426-8411, or email at sanchezlc@email.chop.edu.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children, One-Time Visit Studies

Weight Trajectory with ETI

Use of elexacaftor-texacaftor-ivacaftor ("ETI"), also known as Trikafta, is associated with weight gain in most people with cystic fibrosis (CF) who take this medication. However, some people gain more or less weight than is expected, and this can be either beneficial or problematic based on the individual's starting weight. The goal of this study is to compare factors between children and young adults with CF who have either had robust or minimal weight gain after one year of treatment with ETI.This observational study requires one study visit to CHOP that will last approximately 6 hours.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children, One-Time Visit Studies

Jump back to top