Congenital Hyperinsulinism Center
Children with a congenital hyperinsulinism (HI) diagnosis — or with persistent low blood glucose levels — receive expert evaluation, diagnosis, treatment and follow-up care at the Congenital Hyperinsulinism Center at Children's Hospital of Philadelphia (CHOP).
We have cared for children from 48 states and 18 countries. Our team offers comprehensive support through the process of referring and transporting patients with HI to CHOP.
For more than 50 years, our HI experts have been at the forefront of advances in HI diagnosis and treatment. Our team has deep knowledge of the various types of HI and how to manage them to keep your child safe from the dangerous effects of hypoglycemia.
Because so few adult endocrinologists are familiar with HI, we also offer care to adults with HI.
CHOP's Congenital Hyperinsulinism Center is recognized as a Center of Excellence by Congenital Hyperinsulinism International.
How we serve you
The type of hyperinsulinism your child has guides treatment, including a potential cure. Some children's HI requires long-term medical management that changes over time. We also care for children whose HI is an accompanying symptom of another syndrome.
Conditions we treat
Congenital HI is so rare that only 1 in 25,000 to 50,000 children are diagnosed with HI. Our experts also treat children with other disorders resulting in persistent low blood glucose (also called hypoglycemia).
Why choose CHOP for HI treatment
Experience counts. Most children’s hospitals only see one or two HI cases a year. CHOP has treated more than 1,750 children with congenital HI, making us the world's most active Congenital Hyperinsulinism Center.
Meet your team
Our team of pediatric endocrinologists, surgeons, radiologists, pathologists, anesthesiologists, advanced practice nurses, nurses, social workers, genetic counselors, psychologists, researchers, speech and feeding therapists, and dietitians work together to provide specialized and seamless care.
Our research
CHOP has been home to many breakthroughs in diagnosing and treating HI. Our relentless search to discover new therapies and to better understand the impact HI has on children continues. See De León-Crutchlow Laboratory.
Congenital Hyperinsulinism Center resources
We have created resources to help you find answers to your questions about congenital hyperinsulinism and feel confident in the care you are providing your child.
Patient stories
Resources for professionals
Everything you need to support your patient’s health, created and updated by our CHOP community of experts.
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