Research Studies

Congenital Hyperinsulinism Center Research Studies

Find research studies available to children cared for by the Congenital Hyperinsulinism Center team.
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Clinical trial
Children (2)
Adults (1)
Healthy Controls (1)
MRI/Imaging Studies (1)
One-Time Visit Studies (1)

Clinical Trial Phases
N/A (2)

Recruitment Status
Recruiting (2)

Related Specialties and Programs
Congenital Hyperinsulinism Center (2)

Specialty
Endocrinology (2)

18F-DOPA PET/CT scan for Hyperinsulinism
This study is sponsored by Children's Hospital of Philadelphia Department of Radiology.The purpose of this research is to study 18F-L-Fluoro-DOPA (F-DOPA), a tracer, which is used to take pictures of the pancreas. This imaging test is called an F-DOPA PET scan. The F-DOPA tracer is used to highlight areas of the pancreas that make too much insulin on the PET scan images. The test includes a CT scan (computerized tomography) done at the same time on the same machine, to help define exactly where the highlighted area is located within the pancreas and determine the location of blood vessels and other vital structures.Who can participate:
  • Infants, children and adults with hyperinsulinemic hypoglycemia, diagnosed by a fasting test and/or response to glucagon stimulation
  • Any age, from birth on
  • Requiring surgery to remove part or all of the pancreas

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children, MRI/Imaging Studies, One-Time Visit Studies

Neurocognition in Hyperinsulinism
The purpose of this study is to understand how cognitive function changes over time in children with hyperinsulinism (HI) compared to children who are healthy volunteers. Participants will be asked to complete cognitive function tasks and questionnaires three times over the course of two years: at the start of the study, one year later, and one year after that. Each visit is approximately 2 hours. If you like, you can receive a summary of the results from the tasks. Compensation is provided for your time and effort. 

Phase: N/A

Actively recruiting: Yes

Category: Children, Healthy Controls