Case: Langston is a 12-year-old with sickle cell disease whom you have followed in your practice since infancy.

Avery, a 5-year-old male, presents to the pediatrician for his well-child visit. His parents report that he is growing and developing well, but that they are concerned about recurrent nosebleeds that are happening most nights over the past week.

Researchers from CHOP and Penn are working to perfect 3D models of GI disease and create more personalized treatments for patients.

Fall 2022 saw the loss of two more CHOP luminaries as Ralph Wetmore, MD, former Chief of Otolaryngology, and Audrey Evans, MD, former Chief of Oncology, died in September.

Sickle cell disease (SCD) is the most common inherited blood disorder worldwide; with patients experiencing acute or chronic pain, and increased risk of bacterial infections, organ damage, and stroke.

Welcome back to the annual Chief Residents update column. Our residents have been working so hard during the pandemic and now the unprecedented fall viral surge.

STXBP1-related disorders include gastrointestional and respiratory symptoms in certain patients, according to extensive interviews with caregivers.

A $25 million gift from an anonymous donor to Penn Medicine and Children’s Hospital of Philadelphia (CHOP) will establish the Center for Epilepsy and Neurodevelopmental Disorders (ENDD), accelerating collaborative research in genetic therapies for neurodevelopmental disorders.

Regional and local differences in the diagnosis and treatment of celiac disease affects outcomes for youth.

Dr. Callahan discusses his interest in PVS and his hopes for CHOP’s new program.