Ingredients in COVID-19 Vaccines
This page shows the ingredients in COVID-19 vaccines currently available for use in the U.S.
Find out more about COVID-19 and the vaccines that protect against it.
mRNA versions of COVID-19 vaccines
| Vaccine name* | Antigen | Adjuvant | Stabilizers | Preservatives | Residual byproducts |
|---|---|---|---|---|---|
| Comirnaty | mRNA for the spike protein of SARS-CoV-2 virus | Lipids | Tromethamine, Tromethamine hydrochloride, Lipids, Sucrose | None | None |
| Spikevax | mRNA for the spike protein of SARS-CoV-2 virus | Lipids | Tromethamine, Tromethamine hydrochloride, Acetic acid, Sodium acetate trihydrate, Lipids, Sucrose | None | None |
*Information from package insert dated: 8/2024 (Comirnaty & Spikevax)
Protein-based version of COVID-19 vaccine
| Vaccine name* | Antigen | Adjuvant | Stabilizers | Preservatives | Residual byproducts |
|---|---|---|---|---|---|
| Novavax | Spike protein of SARS-CoV-2 virus | QS-21, Monophosphoryl lipid A | Cholesterol, Potassium chloride, Phosphatidylcholine, Potassium dihydrogen phosphate, Disodium hydrogen phosphate dihydrate, Disodium hydrogen phosphate heptahydrate, Sodium dihydrogen phosphate monohydrate, Sodium chloride, Polysorbate 80 (The pH is adjusted with sodium hydroxide or hydrochloric acid.) | None | Proteins and DNA from cells and vector virus used to grow vaccine virus (Spodoptera frugiperda cells & baculovirus), Lentil lectin, Methyl-α-D-mannopyranoside, Simethicone, Pluronic F-68, Triton X-100, Tergitol |
*Information from package insert dated: 8/2024 (Novavax)
