Other Vaccine Safety Concerns
Check out other pages with related information about vaccine safety. These pages address the items shown below, including vaccine safety, vaccine dosing, fever and vaccines, blood-brain barrier and vaccines, and antibody-dependent enhancement (ADE) and vaccines.
![Black man looking at cell phone](/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/2024-07/Photo-Restricted-VEC-black-man-looking-cell-phone-2624x1720-v01.jpg?itok=77DCspte)
Are Vaccines Safe?
Using different examples, this section examines what it means when we ask the question “Are vaccines safe?” and describes the systems in place to detect rare side effects.
![Vaccine vials and test tubes](/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/2024-07/Photo-Restricted-VEC-vaccine-vials-test-tubes-2624x1720-v01.jpg?itok=YaAFLPFS)
Dosing Safety
People often consider vaccine dosing in the context of medication dosing, but this concept differs between vaccines and medications. This section describes the differences and answers common dose-related questions.
![Boy in bed with fever](/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/2024-07/Photo-Restricted-VEC-boy-in-bed-with-fever-2624x1720-v01.jpg?itok=eguf2Zsj)
Fever and Vaccines
What is a fever? Why do children get fevers after vaccinations? Should I treat my child’s fever?
![Illustration of brain](/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/2024-07/Illustration-Restricted-VEC-brain-only-colored-2624x1720-v01.jpg?itok=hva6rSRm)
Blood-brain Barrier & Vaccines
Some people concerned about vaccine safety wonder whether vaccines can enter the brain and cause neurological conditions. In order to affect the brain, vaccine components would need to reach the brain. Importantly, our brains are protected by a barrier, called the blood-brain barrier (BBB), which keeps foreign substances from entering the brain.
![Illustration of antibody types](/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/2024-07/Illustration-Restricted-VEC-antibody-types-2624x1720-v01_1.jpg?itok=PwGL_cRx)
Antibody-dependent enhancement (ADE) and vaccines
Antibody-dependent enhancement (ADE) occurs when antibodies created during an immune response worsen responses to future encounters with the pathogen. Both diseases and vaccines can occasionally cause ADE; vaccines that led to ADE are no longer in use.
Reviewed on July 17, 2024