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Neurodevelopmental Outcomes in HI
Unrecognized or inadequately treated hyperinsulinism (HI) poses a high risk of adverse neurodevelopmental outcomes due to the combined insult of hypoglycemia and lack of alternate brain fuels.

When Hyperinsulinism is a Family Affair
Inactivating mutations in the beta cell KATP channels are the most common cause of congenital hyperinsulinism (HI), accounting for approximately 60% of all cases with known genotype. The beta cell KATP channels play a very important role in the regulation of insulin secretion by coupling the metabolic state of the cell to membrane potential.
A Day in the Life
Anne Ades, MD, MSEd, serves as Medical Co-Director of CHOP’s Center for Simulation, Advanced Education and Innovation, which uses computerized medical manikins to teach medical procedures. This is a day in her life.

Restoring Reality
CHOP’s First Episode Psychosis Program offers collaborative therapies that put youth on paths to better outcomes.

‘She Was Perfect in That Role’
The children of Vera Barksdale Johnson, CHOP’s first Emergency Department social worker, celebrate her joyful life and groundbreaking career through philanthropy.

Why I Give
Nancy Andrews shares her story about how her son’s multiple surgeries at CHOP inspired her family to give back.

The Flame of Discovery Burns Brightly
For 22 years, collaborative research at CHOP’s Biesecker Pediatric Liver Center has been changing the future for children with serious liver diseases.

Teamwork Makes the Dream Work
The Movement Disorders Program is one of the only programs of its kind in the country and provides life-changing results.

Global Impact of CHOP Radiology: The 2023 Outreach in Ethiopia
n 2008, a partnership was established between the Department of Radiology at Children’s Hospital of Philadelphia (CHOP) and Tikur Anbessa Specialized Hospital (TASH)/Addis Ababa University (AAU), in Addis Ababa, Ethiopia, with the aim of supporting pediatric radiology education during radiology residency at TASH.
Two CHOP Teams Awarded Funds to Study Single Ventricle Congenital Heart Disease
Two research teams in CHOP’s Cardiac Center have been awarded research grants to study single ventricle congenital heart disease.