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Vaccine News & Notes — April 2023
Get details about the Hilleman essay contest for students in grades 6 through 12, and review the science on two "controversies" surrounding COVID-19: masks and lab leak.
Children’s Hospital of Philadelphia Receives $10 Million Grant from the Gilbert Family Foundation to Accelerate Neurofibromatosis Research
Children’s Hospital of Philadelphia (CHOP) today announced that it has received more than $10 million in a series of gifts to fund critical neurofibromatosis research from the Gilbert Family Foundation, a private foundation established by Dan and Jennifer Gilbert to accelerate a cure for neurofibromatosis type 1 (NF1).
For Third Year in a Row, CHOP Fetal Program Wins Award for Excellence in Patient and Family Experience
The Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment (CFDT) at Children’s Hospital of Philadelphia (CHOP) has again won an award from Press Ganey, a healthcare company that evaluates patient satisfaction.
Children’s Hospital of Philadelphia President and CEO Releases New Podcast Season
"The Breakthrough Chronicles” highlights the inspiring stories of CHOP patients and families.
Researchers Show Lorlatinib is Safe, Effective for Patients with High-Risk Neuroblastoma
CHOP researchers have shown that adenovirus proteins use a process called phase separation to coordinate production of viral progeny, which could have broad implications.
Two Focal Lesions: Extra Rare Cases Not so Rare at CHOP
The Congenital Hyperinsulinism Center at Children’s Hospital of Philadelphia, with a high volume of approximately 80 congenital hyperinsulinism (HI) cases a year, sees a large share of unusual cases.
Neurodevelopmental Outcomes in HI
Unrecognized or inadequately treated hyperinsulinism (HI) poses a high risk of adverse neurodevelopmental outcomes due to the combined insult of hypoglycemia and lack of alternate brain fuels.
When Hyperinsulinism is a Family Affair
Inactivating mutations in the beta cell KATP channels are the most common cause of congenital hyperinsulinism (HI), accounting for approximately 60% of all cases with known genotype. The beta cell KATP channels play a very important role in the regulation of insulin secretion by coupling the metabolic state of the cell to membrane potential.
A Day in the Life
Anne Ades, MD, MSEd, serves as Medical Co-Director of CHOP’s Center for Simulation, Advanced Education and Innovation, which uses computerized medical manikins to teach medical procedures. This is a day in her life.
The Flame of Discovery Burns Brightly
For 22 years, collaborative research at CHOP’s Biesecker Pediatric Liver Center has been changing the future for children with serious liver diseases.