Brian R. White, MD, PhD
Areas of expertise: Imaging technique development, General cardiology, Neurodevelopment outcomes
Locations: Main Building, Specialty Care, King of Prussia, Specialty Care, Bryn Mawr
About Brian R. White, MD, PhD
Titles
Attending Physician
Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Certifications
Pediatric Cardiology – American Board of Pediatrics
Pediatrics – American Board of Pediatrics
Awards and Honors
2018, Council on Pediatric and Congenital Heart Disease Travel Grant Recipient: American Society of Echocardiography
2010, Best Poster Award, Optical Society of America Biomedical Optics Congress
2010, O'Leary Neuroscience Prize Finalist, Washington University School of Medicine in St. Louis
2007, Judith Ross Scholarship in Mathematics and Physics, Washington University School of Medicine in St. Louis
2004, John Harvard Scholarship (Top Subset of Dean's List), Harvard University
2004, Edward Purcell Prize (To a Senior for Outstanding Research at the Interface of Physics and Biology), Harvard University
2001, Detur Book Prize (Top Subset of Freshman Class), Harvard University
Leadership and Memberships
Memberships in Professional Organizations
International
2021-present, Society of Photo-optical Instrumentation Engineers
National
2019-present, American Heart Association
2018-present, Society of Pediatric Echocardiography
2018-present, American Society of Echocardiography
2015-present, American College of Cardiology
Editorial and Academic Positions
Editorial Positions
2021-present, Cardiology in the Young, Reviewer
2020-present, Journal of Biomedical Optics, Reviewer
2019-present, Echocardiography, Reviewer
2019-present, BMC Cardiovascular Disorders, Reviewer
2010-present, IEEE Transactions on Medical Imaging, Reviewer
2010-present, Biomedical Optics Express, Reviewer
2009-present, Optics Letters, Reviewer
2009-present, Physics in Medicine and Biology, Reviewer
2008-present, NeuroImage, Reviewer
Education & training
Graduate Degree
PhD - Washington University in St. Louis, St. Louis, MO
Medical Degree
MD - Washington University in St. Louis, St. Louis, MO
Residency
Pediatrics - Children's Hospital of Philadelphia, Philadelphia, PA
Fellowship
Pediatric Cardiology - Children's Hospital of Philadelphia, Philadelphia, PA
Research and Cardiac Imaging - Children's Hospital of Philadelphia, Philadelphia, PA
Publications
Publications
2021
B.R White, J.A. Padawer-Curry, T. Ko, W. Baker, J. Breimann, A.S. Cohen, D.J. Licht, and A.G. Yodh: Wavelength censoring for spectroscopy in optical functional neuroimaging. Physics in Medicine and Biology 66: 065026, 2021.
B.R. White, J.A. Faerber, H. Katcoff, A.C. Glatz, C.E. Mascio, M.S. Cohen: Venous flow variation predicts preoperative pulmonary venous obstruction in children with total anomalous pulmonary venous connection. Journal of the American Society of Echocardiography in press, 2021.
J.A. Padawer-Curry, J. Jahnavi, J.S. Breimann, D.J. Licht, A.G. Yodh, A.S. Co- hen, B.R. White: Variability in Atlas Registration of Optical Intrinsic Signal Imaging and Its Effect on Functional Connectivity Analysis. Journal of the Optical Society of America A 38: 245-252, 2021.
J.A. Padawer-Curry, L.E. Volk, C.D. Mavroudis, T.S. Ko, V.C. Morano, D.R. Busch, T.M. Rosenthal, R.W. Melchior, B.C. Shade, K.L. Schiavo, T.W. Boorady, A.L. Schmidt, K.N. Andersen, J.S. Breimann, J. Jarnavi, K.G. Mensah-Brown, A.G. Yodh, C.E. Mascio, T.J. Kilbaugh, D.J. Licht, B.R. White, W.B. Baker: Effects of Circulatory Arrest and Cardiopulmonary Bypass on Cerebral Autoregulation in Neonatal Swine. Pediatric Research in press, 2021.
2020
B.R. White, J.J. Savla, D.S. Burstein, C.E. Mascio, M.J. O'Connor, A.L. Szwast, L.S. Rogers: Interventricular Septal Hematoma Complicating Placement of a Ventricular Assist Device in an Infant and Support with Bi-atrial Cannulation. JTCVS Techniques 1: 90-92, 2020.
2019
B.R. White, D.Y. Ho, J.A. Faerber, H. Katcoff, A.C. Glatz, C.E. Mascio, P. Stephens, M.S. Cohen: Repair of total anomalous pulmonary venous connection: risk factors for postoperative obstruction. Annals of Thoracic Surgery 108: 122-129, 2019.
B.R. White, D.Y. Ho, L.S. Rogers, S.S. Natarajan: A Standardized Imaging Protocol Improves Quality and Reduces Practice Variability in Echocardiographic Assessment of Ventricular Function by First-Year Pediatric Cardiology Fellows. Echocardiography 36: 1515-1523, 2019.
B.R. White, H. Katcoff, J.A. Faerber, K.Y. Lin, J.W. Rossano, L. Mercer-Rosa, M.J. O'Connor: Echocardiographic assessment of right ventricular function in clinically well pediatric heart transplantation patients and comparison with normal control subjects. Journal of the American Society of Echocardiography 32: 537-544, 2019.
B.R. White, J.A. Padawer-Curry, A.S. Cohen, D.J. Licht, A.G. Yodh: Brain Segmentation, Spatial Censoring, and Averaging Techniques for Optical Functional Connectivity Imaging in Mice. Biomedical Optics Express 10: 5952-5973, 2019.
J.C. Chang, B.R. White, M.D. Elias, R. Xiao, A.M. Knight, P.F. Weiss, L. Mercer-Rosa: Echocardiographic assessment of diastolic function in children with incident systemic lupus erythematosus. Pediatric Cardiology 40: 1017-1025, 2019.
2018
D.Y. Ho, B.R. White, A.C. Glatz, C.E. Mascio, P. Stephens, M.S. Cohen: Postoperative obstruction of the pulmonary veins in mixed total anomalous pulmonary venous connection. Pediatric Cardiology 39: 1489-1495, 2018.
2014
M.S. Hassanpour, B.R. White, A.T. Eggebrecht, S.L. Ferradal, A.Z. Synder, and J.P. Culver: Statistical analysis of high density diffuse optical tomography. NeuroImage 85: 104-116, 2014.
2012
A.T. Eggebrecht, B.R. White, S.L. Ferradal, C. Chen, Y. Zhan, A.Z. Snyder, H. Dehghani, and J.P. Culver: A quantitative spatial comparison of high-density DOT and fMRI cortical mapping. NeuroImage 61: 1120-1128, 2012.
A.W. Bero, A.Q. Bauer, F.R. Stewart, B.R. White, J.R. Cirrito, M.E. Raichle, J.P. Culver, and D.M. Holtzman: Bidirectional relationship between functional connectivity and Aβ plaque deposition in mouse brain. Journal of Neuroscience 32: 4334-4340, 2012.
B.R. White, S.M. Liao, S.L. Ferradal, T.E. Inder, and J.P. Culver: Bedside optical imaging of occipital resting-state functional connectivity in neonates. NeuroImage 59: 2529-2538, 2012.
S.M. Liao, S.L. Ferradal, B.R. White, N.M Gregg, T.E. Inder, and J.P. Culver: High-density diffuse optical tomography of term infant visual cortex in the nursery. Journal of Biomedical Optics 17: 081414, 2012.
2011
B.R. White, A.Q. Bauer, A.Z. Synder, B.L. Schlaggar, J.M. Lee, and J.P. Culver: Imaging of functional connectivity in the mouse brain. PLoS One 6: e16322, 2011.
M. Solomon, B.R. White, R.E. Nothdurft, W. Akers, G. Sudlow, A.T. Eggebrecht, S. Achilefu, and J.P. Culver: Video-rate fluorescence diffuse optical tomography for in vivo sentinel lymph node imaging. Biomedical Optics Express 2: 3267-3277, 2011.
2010
B.R. White and J.P. Culver: Phase-encoded retinotopy as an evaluation of diffuse optical tomography. NeuroImage 49: 568-577, 2010.
B.R. White and J.P. Culver,: A quantitative evaluation of high-density diffuse optical tomography: in vivo resolution and mapping performance. Journal of Biomedical Optics 15: 026006, 2010.
N.M. Gregg, B.R. White, B.W. Zeff, A.J. Berger, and J.P. Culver: Brain specificity of diffuse optical imaging: improvements from superficial signal regression and tomography. Frontiers in Neuroenergetics 2: 14, 2010.
S.M. Liao, N.M. Gregg, B.R. White, B.W. Zeff, K.A. Bjerkaas, T.E. Inder, and J.P. Culver: Neonatal hemodynamic response to visual cortex activity: a high-density near-infrared spectroscopy study. Journal of Biomedical Optics 15: 026010, 2010.
2009
B.R. White, A.Z. Synder, A.L. Cohen, S.E. Petersen, M.E. Raichle, B.L. Schlaggar, and J.P. Culver: Resting-state functional connectivity in the human brain revealed with diffuse optical tomography. NeuroImage 47: 148-156, 2009.
H. Dehghani, B.R. White, B.W. Zeff, A. Tizzard, and J.P. Culver: Depth sensitivity and image reconstruction analysis of dense imaging arrays for mapping brain function with diffuse optical tomography. Applied Optics 48: D137-D143, 2009.
J. Markham, B.R. White, B.W. Zeff, and J.P. Culver: Blind identification of evoked human brain activity with independent component analysis of optical data. Human Brain Mapping 30: 2382-2392, 2009.
2007
B.W. Zeff, B.R. White, H. Dehghani, B.L. Schlaggar, and J.P. Culver: Retinotopic mapping of human visual cortex with high-density diffuse optical tomography. Proceedings of the National Academy of Sciences USA 104: 12169-12174, 2007.
2005
T.C. Chen, B. Cense, M.C. Pierce, N. Nassif, B.H. Park, S.H. Yun, B.R. White, B.E. Bouma, G.J. Tearney, and J.F. de Boer: Spectral domain optical coherence tomography: ultra-high speed, ultra-high resolution ophthalmic imaging. Archives of Ophthalmology 123: 1715-1720, 2005.
2003
B.R. White, M.C. Pierce, N. Nassif, B. Cense, B.H. Park, G.J. Tearney, B.E. Bouma, T.C. Chen, and J.F. de Boer: In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography. Optics Express 11: 3490-3497, 2003.
Books
Book Chapters
2021
B.R. White, D.J. Goldberg, and J. Rychik: Hypoplastic Left Heart Syndrome. Echocardiography in Pediatric and Congenital Heart Disease: From Fetus to Adult (3rd Edition). W.W. Lai, L.L. Mertens, M.S. Cohen, and T. Geva (eds.). Wiley Blackwell, 2021.
2010
B.R. White and J.P. Culver: Noninvasive diffuse optics for brain mapping. Yearbook of Science & Technology. M. Licker (eds.). McGraw-Hill, Page: 264-267, 2010.