Benjamin J. Samelson-Jones
Areas of expertise: Bleeding and clotting disorders, Sickle cell disease, General hematology
About Benjamin J. Samelson-Jones
Benjamin J. Samelson-Jones, MD, PhD, is an attending physician in the Division of Hematology at Children's Hospital of Philadelphia. He is board certified in hematology/oncology and pediatrics. He specializes in treating children with bleeding or clotting disorders, sickle cell disease, and other blood disorders. His current research is focused on gene therapy and immune responses related to Hemophilia.
Dr. Samelson-Jones enjoys this specialty because of the ability to provide care on an ongoing basis throughout childhood. Those long-term relationships are rewarding for both doctor and patient and a key part of CHOP’s culture of care. “I want every family who comes to CHOP to leave feeling that their child received personalized, high-quality, holistic medical care,” said Dr. Samelson-Jones.
Dr. Samelson-Jones earned his medical degree as well as a PhD rom Albert Einstein College of Medicine, Bronx, New York. He continued his training with a residency in pediatrics at Children’s National Health System in Washington, DC and a fellowship in hematology/oncology at CHOP.
Dr. Samelson-Jones is excited about the advances being made in curative therapies for inherited blood disorders. His research is also focused in that area, including projects to investigate the molecular basis of coagulation and immune responses in hemophilia as well as a potential gene therapy for hemophilia.
Titles
Attending Physician
Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Certifications
Hematology – American Board of Internal Medicine
Pediatrics – American Board of Pediatrics
Awards and Honors
2018, Outstanding Poster Presentation Award, American Society of Gene and Cell Therapy
2015, Children’s Hospital of Philadelphia (CHOP) Research Poster Day Prize
2014, Thrombosis-Hemostasis Summit of North America (THSNA) Travel Award
2011, Medical Student Teaching Award
2006, Society of Porphyrins and Phthalocyanines Student Assistance Grant
2006, MS with distinction, Albert Einstein College of Medicine, Bronx, NY
2001, summa cum laude, Amherst College, Amherst, MA
2001, The William Warren Stifler Physics Prize
2000, Dean of Faculty Fellowship for Student Research
1999, The Basset Physics Prize
Leadership and Memberships
Memberships in Professional Organizations
Phi Beta Kappa
Sigma Xi
American Academy of Pediatrics
American Society of Hematology
American Society of Pediatric Hematology and Oncology
Hemostasis and Thrombosis Research Society
International Society of Thrombosis and Haemostasis
Editorial and Academic Positions
Editorial Positions
Peer Reviewer
Public Library of Science (PLOS) One
Haemophilia
Pediatric Blood and Cancer
Journal of Haemostasis and Thrombosis
European Oncology & Haematology
Faculty of 1,000
Pediatric Research
Education & training
Graduate Degree
PhD - Albert Einstein College of Medicine, Bronx, NY
MS - Albert Einstein College of Medicine, Bronx, NY
Medical Degree
MD - Albert Einstein College of Medicine, Bronx, NY
Residency
Pediatrics - Children’s National Health System, Washington, DC
Fellowship
Hematology/Oncology - The Children’s Hospital of Philadelphia, Philadelphia, PA
Publications
Publications
2018
French RA, Samelson-Jones B., Niemeyer GP, Lothrop CD Jr, Merricks EP, Nichols TC, Arruda VR. Complete correction of hemophilia B phenotype by FIX-Padua skeletal muscle gene therapy in an inhibitor-prone dog model. Blood Adv. 2018 Mar 13;2(5):505-508.
Samelson-Jones B., Kramer PM, Chicka M, Gunning III WT, Lambert MP: MYH9-macrothrombocytopenia caused by a novel variant (E1421K) initially presenting as apparent neonatal alloimmune thrombocytopenia. Pediatric Blood and Cancer 2018.
Arruda VR, Doshi BS, Samelson-Jones B Emerging therapies for hemophilia: controversies and unanswered questions. F1000 Research 2018.
2017
George LA, Sullivan SK, Giermasz A, Rasko JEJ, Samelson-Jones B., Ducore J, Cuker A, Sullivan LM, Majumdar S, Teitel J, McGuinn CE, Ragni MV, Luk AY, Hui D, Wright JF, Chen Y, Liu Y, Wachtel K, Winters A, Tiefenbacher S, Arruda VR, van der Loo JCM, Zelenaia O, Takefman D, Carr ME, Couto LB, Anguela XM, High KA. Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant. New England Journal of Medicine 377(23): 2215-2227, 2017.
Arruda VR, Doshi BS, Samelson-Jones B. Novel approaches to hemophilia therapy: successes and challenges. Blood 130(21): 2251-2256, 2017.
Herrmann A, Samelson-Jones B., Brake S, Samelson R.: IVIG-Associated Maternal Pancytopenia during Treatment for Neonatal Alloimmune Thrombocytopenia. American Journal of Perinatology Reports 7: e197-e200, 2017.
2016
Siner, J.I.*, and Samelson-Jones, B.*, Crudele, J.M., French, R.A., Lee, B.J., Zhou, S., Merricks, E., Raymer, R., Nichols, T., Camire R. M., Arruda V. R. (2016) Circumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models. Journal Clinical Investigation Insight: 16: e89371. (*contributed equally to work)
Arruda, V.R. and Samelson-Jones, B. (2016) Gene Therapy for Hemophilia with Inhibitors. Journal of Thrombosis and Haemostasis 14(6): 1121.
2015
Arruda, V.R. and Samelson-Jones, B. (2015) Obstacles and future of gene therapy for hemophilia. Expert Opinion on Orphan Drugs 3:997-1010.
2006
Samelson-Jones B., Yeh S.R. (2006) Interactions between nitric oxide and indoleamine 2,3-dioxygenase. Biochemistry 45:8527-8538.
Wu Z., Jakes K.S., Samelson-Jones B., Lai B., Zhao G., London E., Finkelstein A. (2006) Protein translocation by bacterial toxin channels: a comparison of diphtheria toxin and colicin Ia. Biophys J. 91:3249-3256.
2000
Baluschev S., Friedman N., Khaykovich L., Carasso D., Johns B.*, and Davidson N. (2000) Tunable and frequency stabilized diode-laser with Doppler-free two-photon Zeeman lock. Applied Optics 39: 4970-4974. (* The correct spelling should be Samelson-Jones B.)