Chelsea Kotch, MD, MSCE
Areas of expertise: Pediatric Neuro-Oncology, Neurofibromatosis type 1, Neurofibromatosis-Associated Tumors of Childhood
Locations: Main Building
About Chelsea Kotch, MD, MSCE
Titles
Attending Physician
Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Awards and Honors
2023, Francis Collins Scholar Award in NF Clinical and Translational Research
2022, National Institutes of Health Pediatric Research Loan Repayment Program Award
2022, DHART SPORE Career Enhancement Program Award
2021, Academic Enrichment Fund Award, Children’s Hospital of Philadelphia
2021, Neurofibromatosis Young Investigators’ Forum Travel Award
Leadership and Memberships
Memberships in Professional Organizations
2021-present, Neurofibromatosis Clinical Trials Consortium
2019-present, Society for Neuro-Oncology
2017-present, Children’s Oncology Group
Research Interests
Neurofibromatosis-associated tumors of childhood Pediatric low-grade glioma
Education & training
Graduate Degree
MSCE - Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA
Residency
Pediatrics - Johns Hopkins Hospital, Baltimore, MD
Fellowship
Pediatric Hematology/Oncology - Children’s Hospital of Philadelphia, Philadelphia, PA
Pediatric Neuro-Oncology - Children’s Hospital of Philadelphia, Philadelphia, PA
Publications
Publications
2023
Kotch C, Si S, Desai K, Caminada P, Maria Lo Russo F, Li Y, Liu GT, Avery RA, Fisher MJ. “The Impact of Changes in Gadolinium-Enhancement on Disease Progression in Children with Neurofibromatosis Type 1-Associated Optic Pathway Glioma: A Retrospective Analysis”. J Neurooncol 2023 Sep;164(3):741-747. PMID: 37803102
Kotch C, Elgarten CW, McWhorter J, Schmus C, Wilhelm D, Li Y, Minturn JE. “The Impact of Proactive Gastrostomy Tube Placement on Treatment-Related Outcomes in Young Children with High Grade CNS Tumors”. J Pediatr Hematol Oncol. 2023 Aug 1;45(6):333-338. PMID: 37314947.
Kotch C, Dombi E, Shah AC, Smith KA, Brown S, Li Y, Widemann B, Fisher MJ. “Retrospective Cohort Analysis of the Impact of Puberty on Plexiform Neurofibroma Growth in Patients with Neurofibromatosis Type 1. J Pediatr. 2023 May 25:113513. PMID: 37244583.
Kotch C, Wagner K, Broad JH, Dombi E, Minturn JE, Phillips P, Smith K, Li Y, Jacobs IN, Elden LM, et al. Vinblastine/Methotrexate for Debilitating and Progressive Plexiform Neurofibroma in Children and Young Adults with Neurofibromatosis Type 1: A Phase 2 Study.” Cancers (Basel). 2023 May 5;15(9):2621. PMID: 37174087.
Kotch C, Brosius SN, de Raedt T, Fisher MJ. “Updates in the Management of Central and Peripheral Nervous System Tumors among Patients with Neurofibromatosis Type 1 and Neurofibromatosis Type 2”. Pediatric Neurosurgery.” Pediatric Neurosurgery, 2023. Epub ahead of print. PMID: 36746138.
2022
Kotch C, Avery R, Getz KD, Bouffet E, Gutmann DH, de Blank P, Listernick R, Bornhorst M, Campen C, Liu GT, Aplenc R, Li Y, Fisher MJ. “Risk Factors for Treatment Refractory and Relapsed Optic Pathway Glioma in Children with Neurofibromatosis Type 1”. Neuro Oncol. 2022:8, 1377-1386. PMID: 35018469.
2021
Kotch C, Fisher MJ, Zhong Y, et al. “Atypical Teratoid Rhabdoid Tumor in a Child with Neurofibromatosis Type 2: A Novel Dual Diagnosis”. Cancer Genetics, 2021:262-263, 1-4.
Kotch C, Friedman DF, Wilkins BJ, Samelson-Jones BJ. “Conservative Management of Alloimmune Hemolysis and Cholestasis With Extreme Laboratory Abnormalities”. Pediatrics, 2021;147(2):e20193367
Zhao X, Kotch C, Fox E, et al. “NTRK Fusions Identified in 1,217 Pediatric Tumors: the Frequency, Fusion Partners, and Clinical Outcome”. JCO Precision Oncology, 2021:5 204-214
2019
Matesanz S, Kotch C, Perrone C, et al. “Expanding the MOG phenotype: Brainstem Encephalitis with Punctate and Curvilinear Enhancement”, Neurology: Neuroimmunology & Neuroinflammation, 2019 Nov, 6 (6) e619
Kotch C, Barrett D & Teachey DT. “Tocilizumab for the treatment of chimeric antigen receptor T cell-induced cytokine release syndrome”, Expert Review of Clinical Immunology, 2019 Jun 20:1-10.
Editorials, Reviews, Chapters
2023
Kotch, C & Fisher, MJ (2023). Management of Pediatric Patient with Neurofibromatosis. In Shimony N, Jallo G (Eds.), Pediatric Neurosurgery Board Review: A Comprehensive Guide, (pp 197-212). Springer, Cham.
2022
Mcglynn, J & Kotch, C (2022). Hemostasis & Thrombosis. In R. Tenney-Soeiro (Ed.), Netter’s Pediatrics, 2nd Edition, (pp 483-487). Philadelphia: Elsevier.
2021
Kotch, C & Hogarty, M (2021). Langerhans Cell Histiocytosis and Diabetes Insipidus. In C Alter (Ed.), Diabetes Insipidus in Children: A Pocket Guide (pp. 93-105). Springer International Publishing.
2015
Kotch, C & Yusuf, Z. (2015). Oncology. In H. Hughes & L. Kahl (Ed.), The Harriet Lane Handbook, 21st Edition (pp. 523-542). Philadelphia: Elsevier.