Soma Jyonouchi, MD
Soma Jyonouchi, MD

Soma Jyonouchi, MD

Soma Jyonouchi, MD, is an attending physician with the Division of Allergy and Immunology and the Center for Cornelia de Lange Syndrome and Related Diagnoses at Children's Hospital of Philadelphia.

Areas of expertise: Immunodeficiency in Cornelia de Lange syndrome and other genetic syndromes, Asthma

Locations: Buerger Center for Advanced Pediatric Care

Make an appointment

215-590-2549

About Soma Jyonouchi, MD

Titles

Attending Physician

Assistant Professor of Pediatrics Perelman School of Medicine University of Pennsylvania

Certifications

Allergy and Immunology – American Board of Allergy and Immunology

Pediatrics – American Board of Pediatrics

Education & training

Medical Degree

MD - Medical College of Wisconsin, Milwaukee, WI

Residency

Pediatrics - Children's Hospital and Research Center at Oakland, Oakland, CA

Fellowship

Allergy and Immunology - The Children's Hospital of Philadelphia, Philadelphia, PA

Team affiliations

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Publications

Publications

2019

Primary immunodeficiency considerations in assisted reproductive technology. Sun D. Capucilli P, Jyonouchi S. J Allergy Clinical Immunol Pract 2020 Feb;8(2) 747-747-749. DOI: 10.1016/j.jaip.2019.07.008. Pub 2019 Jul 18.

2017

Immunodeficiencies Associated with Abnormal Newborn Screening for T Cell and B Cell Lymphopenia. Jyonouchi S, Jongco AM, Puck J, Sullivan KE. J Clin Immunol. 2017 May;37(4):363-374. DOI: 10.1007/s10875-017-0388-4 Epub 2017 Mar 28

Phase 1 trial of low-dose interleukin 2 therapy in patients with Wiskott-Aldrich syndrome. Jyonouchi S, Gwafila B, Gwalani LA, Ahmad, M, Moertel C, Holbert C, Kim JY, Kobrinsky N, Roy-Ghanta S, Orange JS. Clin Immunol. 2017 Jun;179:47-53. DOI: 10.1016/j.clim.2017.02.001. Pub 2017 Feb 14. PMID: 2823030. Clinical Trial. 

2011

Pedroza LA, Kumar V, Sanborn KB, Mace EM, Niinkoski H, Nadeau K, et al. Autoimmune regulator (AIRE) contributes to Dectin-1-induced TNF-α production and complexes with caspase recruitment domain-containing protein 9 (CARD9), spleen tyrosine kinase (Syk), and Dectin-1. J Allergy Clin Immunol. Epub 2011 Sep 28. Cited in PubMed; PMID 21962774.

Jyonouchi S, Abraham V, Orange JS, Spergel JM, Gober L, Dudek E, et al. Invariant natural killer T cells from children with versus without food allergy exhibit differential responsiveness to milk-derived sphingomyelin. J Allergy Clin Immunol. 2011 Jul;128(1):102-109.e13. Epub 2011 Apr 1. Cited in PubMed; PMID 21458849.

Jyonouchi S, Forbes L, Ruchelli E, Sullivan KE. Dyskeratosis congenita: a combined immunodeficiency with broad clinical spectrum--a single-center pediatric experience. Pediatr Allergy Immunol. 2011 may;22(3):313-9. doi: 10.1111/j.1399-3038.2010.01136.x. Epub 2011 Feb 1. Cited in PubMed; PMID 21284747.

2009

Jyonouchi S, McDonald-McGinn DM, Bale S, Zackai EH, Sullivan KE. CHARGE (colomba, heart defect, atresia choanae, retarded growth and development, genital hypoplasia, ear anomalies/deafness) syndrome and chromosome 22q11.2 deletion syndrome: a comparison of immunologic and nonimmunologic phenotypic features. Pediatrics. 2009 May;123(5):3871-7. Cited in PubMed; PMID 19403480.

Jyonouchi S, Brown-Whitehorn TA, Spergel JM. Association of eosinophilic gastrointestinal disorders with other atopic disorders. Immunol Allergy Clin North Am. 2009 Feb;29(1):85-97, x. Cited in PubMed; PMID 19141344.

Patient experience rating

(based on 172 submissions)
  • Clear Explanation
    4.8 of 5
  • Showed Concern
    4.8 of 5
  • Included in decisions
    4.8 of 5
  • Would recommend
    4.8 of 5
  • Discussion of Proposed Treatment
    4.8 of 5
Learn about the patient experience rating system

Comments

  • Hands down the best allergist experience we've had so far thank you
    5 of 5
    Jun 29, 2024

  • Dr. Jyonouchi quickly pinpointed the cause of my daughter's immunological challenges and prescribed an effective treatment. During both of our appointments with him, he took his time, listened to all of our concerns, and answered every question.
    5 of 5
    May 10, 2024

  • He is the absolute best doctor we could ask for
    5 of 5
    Mar 25, 2024

  • Great experience! All questions and concerns answered. Very informative. Doctor showed care and concern to our son!
    5 of 5
    Dec 11, 2023

  • Maybe our favorite doctor we have seen. Always patient and thoughtful and takes time to answer all of our questions.
    5 of 5
    Dec 04, 2023

  • Dr. Jyonouchi was kind and patient with my daughter. She didn't want the visit to be over!
    5 of 5
    Sep 04, 2023

  • Very through explaining everything. Listened to me and my husband. Didn't rush. Took his time with our complex son
    5 of 5
    Sep 03, 2023

  • The Doctor always takes the time to sit and explain everything. We never feel rushed.
    5 of 5
    Jun 29, 2023

  • Dr. Jyonouchi was great. Kind and very good with my son. Answered my questions and did not seem rushed, though I'm sure he was busy!
    5 of 5
    May 15, 2023

  • Through and not rushing
    5 of 5
    Apr 15, 2023

  • He had read through my daughter's records prior so our appointment was very streamlined and he was able to use that prior info to create a plan that worked for our family moving forward.
    5 of 5
    Mar 21, 2023

  • Calm and very informative
    5 of 5
    Mar 20, 2023
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About the Patient Experience Rating System

The Patient Experience Rating is an average of all responses to the care provider related questions shown above from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question. Responses are measured on a scale of 1 to 5 with 5 being the best score. We are committed to true transparency. However, to ensure the comments are fair and correctly attributed, we review each one before posting to the website. We exclude entire comments that disclose patient’s protected health information, are off-topic, or include other confidential or inappropriate content. Comments will appear on provider bios only if providers have a minimum number of comments. Comments are shared internally for education purposes to ensure that we are doing our very best for the patients and families for whom we are privileged to care. The comments are submitted by patients and families and reflect their views and opinions. The comments are not endorsed by and do not reflect the views of Children’s Hospital of Philadelphia.