Immunology Program
The Immunology Program at Children's Hospital of Philadelphia (CHOP) provides sensitive, patient-centered care to children and young adults with immune deficiencies. Our team works closely with families to educate them about immune deficiencies and offers various immunology therapies that may be recommended for their children.
Our program works with CHOP’s Immunology Laboratory to provide the full range of advanced diagnostic testing to determine an accurate diagnosis for your child and the challenges they may face. Our goal is to identify therapies that could better manage your child’s illness, improve their symptoms and help them become more independent.
We will also connect you with other families facing similar medical challenges who understand your family’s experience and changing medical needs.
How we serve you
Children with primary immune deficiency disease may experience recurrent infections, unusual infections and autoimmune diseases. With advanced diagnostic tools, our expert staff can provide an accurate diagnosis and personalize a treatment plan to improve your child’s quality of life.
Conditions we treat
Our program treats children with primary and secondary immune deficiencies and autoimmune diseases, including those listed below.
- Antibody deficiency disorders
- CHARGE syndrome
- Children with unusual autoimmune disease
- Children with very early onset inflammatory bowel disease
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Chromosome 22q11.2 deletion - Chronic granulomatous disease
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Common variable immunodeficiency (CVID) -
Cornelia de Lange syndrome - Hyper IgE syndrome and other conditions of severe allergy
- Innate immunity disorders
- Metabolic conditions associated with immunodeficiency
- Mitochondrial diseases associated with immunodeficiency
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Severe combined immunodeficiency (SCID) -
VEO-IBD
Why choose CHOP for immunology therapy
We offer the most up-to-date therapies for patients with primary immunodeficiency disorders and work closely with related teams – such as bone marrow transplant, cellular therapy and the transition clinic – to best support patients.
Meet your team
Experts in the Immunology Program take a team approach to your child's care. This allows us to quickly respond to your questions and concerns.
Our locations
You can visit the Immunology Program at various locations across the region.
Our research
The Immunology Program participates in longitudinal registries of patients with immune deficiencies over prolonged periods of time to determine the best treatments for these diseases.
Immunology Program resources
We have created resources to help you find answers to your questions and feel confident with the care you are providing your child.
Patient stories
Events
7th Annual CHOP Immune Dysregulation Symposium: Rub Some DIRT In It – An Immune Dysregulation Approach to Infection
Wednesday, Apr 30, 2025
Your donation changes lives
Philanthropic donations fuel breakthrough discoveries, innovative care and pioneering treatments in the Division of Allergy and Immunology at CHOP.
