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Research Studies

Obstructive Sleep Apnea Research Studies

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Clinical trial
Children (4)
Adults (1)
MRI/Imaging Studies (1)

Clinical Trial Phases
Phase II (2)
Phase III (1)
N/A (1)

Recruitment Status
Recruiting (4)

Related conditions
Obstructive Sleep Apnea (4)
Trisomy 21 (Down Syndrome) (2)
Beckwith-Wiedemann syndrome (1)

Related Specialties and Programs
Division of Pulmonary and Sleep Medicine (4)
Sleep Center (4)

Specialty
Pulmonology (4)

Down Syndrome and Sleep Apnea Study (DOSA)
This research study is being conducted to look at oxygen as a treatment of obstructive sleep apnea (OSA) in children with Down syndrome. The main reason for the study is to show how 6 months of oxygen treatment while sleeping affects the participants sleep, quality of life, breathing, heart and if it makes the participant feel better.

Phase: Phase II

Actively recruiting: Yes

Category: Children

Conditions: Trisomy 21 (Down Syndrome), Obstructive Sleep Apnea

Home Sleep Apnea Testing Following Adenotonsillectomy (HOM-Kids Study)

This research study aims to compare the accuracy of a home sleep apnea testing device (used as part of a home sleep study) for diagnosing obstructive sleep apnea in children who have had their adenoid and/or tonsils surgically removed, with an in-lab overnight sleep study. Children eligible for this study must be between the ages of 5 and 12. Participants will be randomly assigned to determine the order in which they complete the two sleep studies. After both the in-lab and home sleep studies are completed, families will be asked to complete questionnaires assessing the acceptability of home sleep apnea testing, as well as their preference between the two testing methods.

Phase: Phase II

Actively recruiting: Yes

Category: Children

Conditions: Obstructive Sleep Apnea

Home Sleep Apnea Testing in Children (HATCh) Study

The purpose of this research is to compare home sleep apnea testing (HSAT) to in-lab overnight sleep study. We want to see if HSAT in children can be an alternative to in-lab sleep study for the diagnosis of obstructive sleep apnea. 

Phase: Phase III

Actively recruiting: Yes

Category: Children

Conditions: Trisomy 21 (Down Syndrome), Obstructive Sleep Apnea

Sleep Apnea in People with Beckwith-Wiedemann Syndrome
Children and adults with Beckwith-Wiedemann syndrome may be at increased risk for sleep apnea than other children. This risk may be due to a larger tongue size, but currently it is not known how to predict who need to be evaluated for sleep apnea. Some people with Beckwith-Wiedemann syndrome have tongue reduction surgery, but the effect of this procedure on sleep apnea is not known. This study seeks to understand how the upper airway anatomy contributes to sleep apnea in people with Beckwith-Wiedemann syndrome, including after tongue reduction surgery in people who have that procedure. The study includes a physical exam, medical record review (including surgical history), and upper airway MRI. For those participants who have not had a clinical sleep study, one will be done as part of this study.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children, MRI/Imaging Studies

Conditions: Obstructive Sleep Apnea, Beckwith-Wiedemann syndrome