Abdominal wall defects (AWD) are rare, complex anomalies whose causes are unknown. Optimal outcomes depend on the ability to orchestrate many factors.

The Children's Hospital of Philadelphia has initiated a standard practice of continuous intraoperative echocardiographic monitoring for all fetuses undergoing myelomeningocele repair.

Fetal closure of an MMC is technically more challenging than the standard postnatal closure. The access is smaller, the structures are smaller and more delicate, the placode must be handled with more care, avoiding blood loss is critical, and the surgery must be performed quickly to limit the exposure of the fetus to the extrauterine environment.

Myelomeningocele (MMC) poses a diagnostic and therapeutic challenge. A thorough and detailed examination of the entire fetus, with visualization of every spinal segment, is necessary.

Before the start of the Management of Myelomeningocele Study (MOMS) in 2003, an initial group of 58 patients at CHOP underwent in utero repair of their myelomeningocele between 21 and 25 weeks' gestation. Urologic results after fMMC repair are discussed here.

The CFDT Center at CHOP recently reviewed outcomes for fetal MMC repair since the MOMS results were reported, from referral and evaluation through surgery, delivery and neonatal discharge.

The Children’s Hospital of Philadelphia is the first children’s hospital to be selected as a finalist for the 2014 Foster G. McGaw Prize.

The Children’s Hospital of Philadelphia unveiled a portrait of Ruth M. and Tristram C. Colket Jr. in October to honor their more than 40 years of extraordinary dedication to CHOP.

Researchers at The Children's Hospital of Philadelphia improved motor function and brain abnormalities in animals with a form of Huntington’s disease, a severe neurological disorder.

Stevens-Johnson syndrome (SJS) is a lifethreatening cutaneous immune-mediated reaction involving blistering and desquamation of the skin and mucous membranes.