Summer 2021 saw the Congenital Hyperinsulinism Center at Children’s Hospital of Philadelphia care for two newborn girls who had the focal form of hyperinsulinism (HI).

Diva De León-Crutchlow, MD, MSCE, assumed the role of Director of the Congenital Hyperinsulinism Center in 2013 and was named Chief of the Division of Endocrinology and Diabetes in 2018.

CHOP researchers have found that indicators of lower socioeconomic status are associated with an increased risk of cleft lip with or without cleft palate.

Aberrant splicing leads to downregulation of CD22 in pediatric B-ALL, rendering malignant cells resistant to the effects of CD22-directed immunotherapies.

CHOP's Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE) study was recently awarded funding from the Patient-Centered Outcomes Research Institute (PCORI). PRESERVE is a three-year, multi-institutional clinical trial evaluating blood pressure management and urine protein monitoring strategies to preserve kidney function in pediatric chronic kidney disease (CKD) patients.

Why your teen’s doctor wants to speak privately with them — and why you should welcome it as they begin to take on their own health autonomy.

Parents are usually blindsided when they find out that their child has congenital hyperinsulinism (HI), a rare genetic disorder that depresses blood sugar to dangerously low levels.

Low blood sugar is one of the symptoms of Kabuki syndrome, a genetic disorder that affects multiple systems in the body but can be tricky to diagnose.

Researchers have unlocked patterns to improve the diagnosis of the most common epigenetic childhood cancer disorder.

New research has identified several new clinical considerations and provides guidance for proper diagnosis and management of very rare disease.