A team of gene therapy researchers has reported on a highly active gene variant that achieved sustained factor levels in 10 adults, with no adverse effects.

CHOP/Penn Medicine team is first to show massive cortical reorganization is reversible in a child.

Can Ficicioglu, MD, PhD, a physician-scientist with expertise in genetic disorders, was appointed to a statewide Rare Diseases Advisory Council by the PA Department of Health.

How can you get your kids to eat heart-healthy food? Check out these helpful tips and recipe ideas.

Falls are the leading cause of unintentional injuries, and are responsible for half of childhood traumatic brain injuries. Find practical tips for reducing the risk of falls for children of different ages.

A genetic tendency for later puberty causes lower bone mineral density. This effect may raise the risk of osteoporosis and fractures later in life.

After 485 days at Children’s Hospital of Philadelphia, formerly conjoined twins, Erin and Abby Delaney, were discharged to return home to North Carolina, just in time for Thanksgiving.

Breakthroughs happen every day at Children’s Hospital of Philadelphia — thanks to supporters like you! We want to thank you for transforming children’s lives and making tomorrow’s breakthroughs possible for children today.

A 14-year-old male, began experiencing pain in his lower left leg during a period of intense training for a cycling event. When the pain remained after training, examination showed full range of motion of the knee and mild tenderness over the upper tibia. An X-ray was concerning for a lesion in the upper tibia. What's his diagnosis?

A CHOP expert in childhood hearing loss co-led a study detailing how a mutated gene disrupts normal development in the inner ear. The research may offer clues to designing future treatments.