STRIVE for Kids Program
The STRIVE for Kids Program at Children's Hospital of Philadelphia (CHOP) combines expertise from a team of endocrinologists, psychologists, geneticists and more to support comprehensive care for people with differences in sex development (DSD), variations in sex characteristics (VSC) and other conditions that may affect genitourinary (GU) development or reproduction.
Your child may be referred to the STRIVE for Kids Program at CHOP if they have features or symptoms that could be related to DSD, VSC, a lack of or stalled puberty (also called pubertal concern), or other endocrine and urologic concerns.
This clinic, the Supportive Team approach to ReproductIVE (STRIVE) variations program, combines the expertise from the Division of Endocrinology, the Adrenal and Puberty Center, Psychology, Urology and the Roberts Individualized Medical Genetics Center.
How we serve you
We offer diagnostic, management and treatment services to individuals with differences in sex development, as well as provide support to patients and families.
Conditions we treat
Our program treats children with differences in sex development and genitourinary development, including those with ambiguous genitalia, intersex traits and mosaic Turner syndrome, among others.
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Androgen insensitivity syndrome -
Ambiguous genitalia - 46, XY or 46, XX gonadal dysgenesis
- 46 XX, SRY+
- Ovotesticular DSD
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Ectopic pituitary -
Hypopituitarism - 5-alpha reductase deficiency
- Intersex traits
- Rare genetic conditions that affect testosterone biosynthesis
- Severe hypospadias (also called penoscrotal hypospadias)
- Microphallus (also called micropenis)
- Clitoromegaly
- Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome
- Testicular regression syndrome (bilateral vanishing testis)
- Persistent Müllerian duct syndrome
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Delayed puberty -
Hypogonadism -
Kallmann syndrome - Testicular failure
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Primary amenorrhea - Primary ovarian failure
- Hypergonadotropic hypogonadism
- Anti-Müllerian hormone deficiency
- Sex chromosome differences (sex chromosome chimerism, mosaic Turner syndrome, mixed gonadal dysgenesis)
Why choose the STRIVE Program
The STRIVE for Kids Program at CHOP is one of the busiest programs in the country working with children with differences in sex development (DSD) and genitourinary (GU) development.
Meet your team
Our team works with professionals from various departments at CHOP to ensure continuity of care and individualized treatment for children with differences of sex development. We offer counseling and support from birth through adulthood.
Our locations
You can visit staff from the STRIVE for Kids Program at our Philadelphia and King of Prussia campuses.
Resources for professionals
Everything you need to support your patient’s health, created and updated by our CHOP community of experts.
Your child’s appointment
Patients come to the STRIVE for Kids Program for evaluation and second opinions. While most families are referred to us by pediatricians or specialists, families can directly request an evaluation.
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