Three pediatric sports medicine leaders from CHOP share perspectives about how youth athletes have changed, how the field has evolved, and predictions for the future.

Researchers at Children’s Hospital of Philadelphia (CHOP) and the Children’s Oncology Group (COG) found that larotrectinib, an oral drug that stops cancer-cell growth, was highly effective in pediatric patients with newly diagnosed infantile fibrosarcoma (IFS) or other solid tumors that have a neurotrophic receptor tyrosine kinase (NTRK) gene fusion without a known acquired resistance mutation. The study, published today in the Journal of Clinical Oncology, is the first COG trial to test precision medicine in a front-line setting across all different types of solid tumors based on a genetic biomarker rather than histology. It is poised to redefine the approach to treatment for newly diagnosed fibrosarcoma and other solid tumors with the NTRK gene fusion, potentially reducing or eliminating the need for these patients to receive chemotherapy.

Novel study emphasizes the need for improved training to recognize key behavior differences in this patient population

Researchers at Children’s Hospital of Philadelphia (CHOP) and the Children’s Oncology Group (COG) announced the results of a Phase 3 study that demonstrated adding the bi-specific T-cell engager, blinatumomab, to chemotherapy for newly diagnosed National Cancer Institute (NCI) standard risk (SR) B-cell acute lymphoblastic leukemia (B-ALL) pediatric patients significantly improves survival outcomes. The results were published today in the New England Journal of Medicine and will be presented at the 66th American Society of Hematology (ASH) Annual Meeting & Exposition on December 8.

Find info about: VMP's essay contest for students, VEC's new YouTube channel and video series, a new critical thinking resource, and when politicization of science results in lack of access to healthcare resources.

See how well you do answering questions about information shared in 2024 Parents PACK newsletter articles.

Risk of transmission of the rotavirus vaccine is extremely low and poses very minimal risk to NICU babies

In recognition of her impact on child health in Consuelo and beyond, Ramona Cordero was awarded the inaugural Melissa Ketunuti Basselier Prize in Global Child Health.

This study aims to expand use of supraglottic airways as a potential approach for better outcomes for newborns who require resuscitation

The Lactation Department of the Children’s Hospital of Philadelphia (CHOP) offers a bi-annual internship to individuals who are preparing to take the International Board Lactation Consultant Exam.