Researchers in CHOP’s Pediatric Heart Valve Center have found that the neurotransmitter serotonin can adversely affect the heart’s mitral valve, contributing to a heart disease known as degenerative mitral regurgitation.

In an effort to encourage families and communities to take an active role in protecting children from gun violence, leading healthcare systems across Pennsylvania, Delaware and New Jersey have joined thousands of hospitals and health associations in a nationwide public awareness and education campaign.

This novel method uses fruit flies and zebra fish to validate the function behind a gene associated with sleep regulation and may be a target for studies on sleeping disorders.

CHOP researchers have led an international group of experts in developing new guidelines for neonatal resuscitation research.

CHOP researchers have found that before the wide availability of vaccines, newborns were infected with SARS-CoV-2 at variable rates and without apparent short-term effects.

Through collaboration with research partners, patients, foundations, and community members, we are working to defeat childhood brain cancer and find better treatments for current patients. Read about recent milestones we’ve hit to accelerate pediatric brain tumor research.

Find out about an association between COVID-19 vaccination and length of menstrual cycle; learn about a new video series, "Vaccine-Preventable Disease: The Forgotten Story," and more.

In this video feature article, Dr. Offit discusses the concept of “immunity debt” (also called “immunity gap”). Find out more.

Read this case study about integrating precision medicine into the standard of care for children with thyroid cancer.

See why Dr. Lori Handy views vaccines as strengthening the immune system instead of weakening it.