Lacking effective drug treatments, patients with mitochondrial disease may use many vitamins and supplements — most of which are unregulated and untested.

A breakthrough therapy has its genesis in more than 10 years of research conducted at Children's Hospital of Philadelphia.

A team of gene therapy researchers has reported on a highly active gene variant that achieved sustained factor levels in 10 adults, with no adverse effects.

Physicians who see patients with mitochondrial disease have a practical new tool: the first published care standards to guide clinical care.

Mitochondria, your cells’ power engines, could pay a key role in the development of autism spectrum disorder.

CHOP’s Douglas Wallace, a world-renowned pioneer in mitochondrial biology, received the 2017 Benjamin Franklin Medal in Life Science at the Franklin Institute.

Amid a cascade of DNA data, a CHOP genetics expert co-led a Think Tank that made recommendations to help families and clinicians understand and use this information.

Mitchondria, the tiny structures that are power plants of our cells, may have helped humans and other mammals adapt and evolve over the eons.

A puzzling multisystem disorder leads to discovery of a new genetic syndrome, and an end to families’ "diagnostic odysseys."

A new CHOP study has uncovered several gene networks with potentially important roles in autism. These networks may offer attractive targets for developing new autism treatments.