This study aims to collect data from patients seen at CHOP, CHOP's 3550 Market St. primary care location, Penn, or from the surrounding communities. If you choose to participate, we will take an optional blood, saliva, and/or stool sample, have you complete computer testing that measures things like your reaction time and your memory, have you complete questionnaires, and we will interview you and your parent or legal guardian to ask questions about your life experiences and perceptions, and past and current mental health.

The purpose of this study is to test the safety of an investigational medicine called ML-004 and how it might affect communication, behavior, and other symptoms of autism spectrum disorder (ASD). This medication is investigational because it has not been approved by the FDA for the treatment of symptoms associated with autism.

You may qualify if you:

• Are 12 to 17 years old
• Have an autism diagnosis
• Have a designated care/study partner able to attend every visit and answer questions about the participant. This person does not need to be the participant's parent or guardian. This person should have significant contact with them and can support them for the duration of the study.
• Are able to swallow the study medication (tablet)

PEDSnet and DBPNet seek youth (13-24), parents, and clinicians/scientists for the Intellectual and Developmental Disabilities (IDD) Research Prioritization Study. The goal is to develop a prioritized list of research questions that will immediately impact patient health outcomes, focusing on children with IDD.
Participants will answer open-ended questions on Viva Engage, a Microsoft platform, to share their thoughts and opinions. The study is entirely online, and parents and youth will be compensated for their time. To participate or learn more, complete our eligibility screener.

The mission of SPARK is to ignite research at an unprecedented scale to improve lives by advancing our understanding of autism. To join this national autism research cohort, individuals with a professional diagnosis of autism and their biological family members will be asked to share information about their medical and family history, as well as provide a DNA sample.