Department of Biomedical and Health Informatics (DBHi) News

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Children’s Hospital of Philadelphia Study Highlights Deeper Understanding of Genetic Links between Childhood Speech and Language Disorders

Researchers at Children’s Hospital of Philadelphia (CHOP) announced the results of a new study highlighting significant genetic links in speech and language disorders in children.

New Computational Tool Tracks Transfer of Mitochondria from T Cells to Cancer Cells

Oct 9, 2023

CHOP researchers have developed a computational tool to determine which cells in patient tumor samples receive mitochondria from T cells.

CHOP Researchers Develop Versatile and Low-Cost Technology for Targeted Long-read RNA Sequencing

Aug 15, 2023

CHOP researchers have developed a versatile and low-cost technology for targeted sequencing of full-length RNA molecules.

New Computational Tool Identifies Novel Targets for Cancer Immunotherapy

May 17, 2023

CHOP and UCLA researchers have created a tool that can discover tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets.

CHOP Researchers Use Novel Technique to Analyze 53 Million Points of Clinical Data

Apr 6, 2023

Findings demonstrate how a new computational method could effectively analyze phenotypes and identify similarities among patient populations.

CHOP Researchers Develop New, More Accurate Computational Tool for Long-Read RNA Sequencing

Jan 20, 2023

CHOP researchers have developed a new computational tool that can more accurately discover and quantify RNA molecules from these error-prone long-read RNA sequencing data.

CHOP Helps Develop Platform to Speed Up Drug Development for Kids with Cancer

Aug 4, 2022

CHOP has helped launch NCI-backed “Molecular Targets Platform” to streamline and catalyze drug development by harmonizing data about pediatric cancer targets and pathways.

CHOP Study Aims to Reveal How Genetics, Environment Contribute to Psychiatric and Cognitive Outcomes

May 13, 2022

CHOP researchers have integrated environmental, genetic, and imaging data to better understand which factors might be clinically relevant when it comes to psychiatric and cognitive outcomes.

CHOP Researchers Develop New Computational Tool to Interpret Clinical Significance of Cancer Mutations

May 6, 2022

CHOP researchers have developed new software called CancerVar, which helps researchers assess the clinical impacts of over 13 million somatic cancer mutations.

Using Social Cues to Adjust Conversational Behavior May Be Challenging for Autistic Children and Teens

Mar 15, 2022

Learning to adjust talkativeness could be an important growth opportunity for verbally fluent people with autism.

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