The primary objective of this study is to collect biospecimens to conduct protein biomarker studies in patients with heart failure requiring advanced therapies such as OHT and VAD. A dedicated heart failure biospecimen repository will allow the Cardiac Center to be at the forefront of molecular sub-phenotyping to improve mechanistic understanding, clinical care, and trial design.

The study will measure both myocardial dysfunction and inflammation as it is related to the severity of cardiac arrest, and their association with post-cardiac arrest morbidity and mortality. The study will also determine how the change in both myocardial function and inflammatory markers over time is association with outcomes.