First Child to Receive Revolutionary CAR T Therapy Celebrates 10 Years Cancer Free
May 11, 2022
Emily Whitehead, now 17, received life-saving treatment at CHOP, transforming the field of cancer immunotherapy.
Cancer Immunotherapy Program News
Every person on your child’s team has the same goal: to give your child the best possible care. We provide medical care, emotional support and much more. Each team member has extensive experience in the treatment of children using immunotherapy.
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Emily Whitehead, First Pediatric Patient to Receive CAR T-Cell Therapy, Celebrates Cure 10 Years Later
May 11, 2022
Whitehead received life-saving treatment at CHOP, under the care of Dr. Stephan Grupp, transforming the field of cancer immunotherapy.
CHOP Brings Together Experts to Discuss Precision Medicine in Pediatric Cancer Care
Mar 18, 2022
More than 250 experts gathered in Philadelphia and virtually to discuss the latest scientific advancements and breakthroughs in pediatric precision medicine oncology.
CHOP/Penn Study Shows CAR-T Cells Remain Active a Decade After Infusion
Feb 2, 2022
A new study in Nature has documented the longest persistence of CAR T cell therapy to date.
Aberrant Splicing of CD22 in Acute Lymphoblastic Leukemia Underlies Resistance to Immunotherapy
Jan 4, 2022
Aberrant splicing leads to downregulation of CD22 in pediatric B-ALL, rendering malignant cells resistant to the effects of CD22-directed immunotherapies.
Stephan Grupp, MD, PhD, a Panelist at Distinguished Conference About National Cancer Act
Dec 13, 2021
A cell and gene therapy expert, Grupp discussed progress in clinical care in the 50 years since the legislation was signed.
Positive Preliminary Data on CRISPR Treatment for Blood Diseases
Aug 10, 2021
A collaborative team of researchers, including Dr. Stephan Grupp, recently presented preliminary data showing that a CRISPR-based gene-editing therapy for inherited blood disorders is safe and effective.
CHOP Researchers Develop Humanized CAR T-Cell Therapy that Shows Potential for Patients with Relapsed B-ALL
Jun 28, 2021
The treatment modifies a domain in the CAR that targets CD19, making it look more human and therefore less likely to be rejected by patients.
CHOP Gene Therapy Experts Profiled in Philadelphia Magazine
May 12, 2021
CHOP researchers were interviewed as a part of a comprehensive article about cell and gene therapy in Philadelphia Magazine.
Shannon Maude, MD, Discusses Unique Challenges Facing CAR-T Cell Therapy in Healio Article
Feb 26, 2021
Dr. Shannon Maude, an attending physician in the Cancer Center at CHOP, provided expert insight on the unique challenges facing CAR T-cell therapy for pediatric indications in an article published in Healio’s February issue of Cell Therapy Next.