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Cancer Center News

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A Heartfelt Haven: The 3 South Playroom Refresh

Dec 11, 2024

The 3 South Playroom in CHOP’s Main Building officially reopened after a renovation funded by generous support from Dancing While Cancering, the Maddie Kramer Foundation.

New Research from Children’s Hospital of Philadelphia to Transform Standard of Care Across the Globe for Newly Diagnosed Children with B-cell Acute Lymphoblastic Leukemia

Dec 7, 2024

Researchers at Children’s Hospital of Philadelphia (CHOP) and the Children’s Oncology Group (COG) announced the results of a Phase 3 study that demonstrated adding the bi-specific T-cell engager, blinatumomab, to chemotherapy for newly diagnosed National Cancer Institute (NCI) standard risk (SR) B-cell acute lymphoblastic leukemia (B-ALL) pediatric patients significantly improves survival outcomes. The results were published today in the New England Journal of Medicine and will be presented at the 66th American Society of Hematology (ASH) Annual Meeting & Exposition on December 8.

Children’s Hospital of Philadelphia Researchers Find Pediatric Brain Tumor Survivors Are At-Risk for Social Deficits, Fewer Friendships, and Poor Peer Relationships

Nov 26, 2024

In a recent study, researchers at Children’s Hospital of Philadelphia (CHOP) demonstrated that children treated for brain tumors face persistent social challenges, including limited friendships and reduced peer acceptance, extending into adulthood. The study is the first to link disruptions in white matter connectivity to impaired social functioning in survivors of pediatric brain tumors.

Dr. Yael Mossé Named a Recipient of the 2024 Penn Medicine Awards of Excellence

Nov 12, 2024

Yael Mossé, MD, received the William Osler Patient Oriented Research Award, which was established in 1996 to honor Osler, a “Father of Clinical Medicine” who, in the 1800s, revolutionized clinical teaching and patient-oriented research at the Perelman School of Medicine at the University of Pennsylvania.

Researchers at Children’s Hospital of Philadelphia Highlight Role of Alternative Splicing in Chemotherapy Resistance

Researchers at Children’s Hospital of Philadelphia (CHOP) have elucidated the significant role that alternative splicing – a process whereby a single gene produces multiple proteins by rearranging its messenger RNA segments in different combinations – plays in resistance to chemotherapy in relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL). The study published today in the journal Cancer Research.

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