This research is studying a vaccine against Mpox (formerly known as monkeypox) that is FDA approved for adults but not yet approved for children. The goal of the study is to determine if the vaccine protects children just as well as it protects adults. The study is also looking at the safety of the vaccine. This study is open to healthy adolescents, ages 12-17. In addition, adolescents with certain immunodeficiency diseases or other conditions, that are well controlled, are eligible to participate.

This study wants to know about the problems that Black or African American teenagers with type 1 diabetes (T1D) and their families face. It also wants to see how these problems affect their feelings, behavior, and how they get along with others. The study will find out how well they can handle T1D and adapt to it. It will also learn how good things like being strong, family, and where they live might help young people who have to deal with hard things. This includes how well they handle their feelings, behavior, relationships, and T1D care.

Researchers at CHOP are trying to improve outcomes in the treatment of adolescents with anorexia nervosa. Eligible families will receive Family Based Treatment for anorexia nervosa. Some adolescents with anorexia nervosa will also receive Cognitive Remediation Therapy (a treatment that increases flexible thinking). Both parents are required to participate and any siblings living at home are asked to come to the first four treatment sessions. Families will receive treatment for approximately 6 months and will be asked to complete number of assessments during treatment and at two time points after treatment ends.