Leukodystrophies are inherited disorders of the white matter of the brain and spinal cord that can cause problems with movement, speaking, vision, hearing, and overall development. These disorders are difficult to recognize and diagnose. The Leukodystrophy Center at Children's Hospital of Philadelphia (CHOP) provides comprehensive clinical care, diagnostic testing and the most advanced treatments available to infants, children and adolescents living with these inherited white matter diseases. In this video, hear from clinicians and patient families who have been cared for by CHOP’s Leukodystrophy Center, and learn how the team is using cutting-edge research to better understand the causes of leukodystrophy and advance clinical care.