MRI Assessment of NAD+
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Description
NAD+ (nicotinamide adenine dinucleotide) is an important substance found in the body that plays a role in energy metabolism and overall health. The purpose of this research study is to test the performance of a new magnetic resonance imaging (MRI) technique (spectroscopy) to measure NAD+ metabolism in brain and skeletal muscle. MRI provides pictures of the inside of the body and information about chemicals the body makes.We are seeking to enroll males and females with Friedrichs Ataxia (FA) as well as healthy matched volunteers, 18 years of age and above. Pregnant females excluded for safety purposes.
Eligibility and criteria
IRB Number:
23-020866
Eligible age range:
Clinical trial phase:
N/A
Official title:
What to expect
- Fasting Labs
- Questionnaires about Fatigue and Physical Activity (15 - 30 Minutes)
- MRI (Up to 90 Minutes)
A sub-set of participants will be invited to return for additional study visit(s) to complete MRI scans with different sequences (brain NAD+, calf NAD+).
Related specialties
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