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Allo CD7 CAR WU-CART-007

Allo CD7 CAR WU-CART-007

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If you are interested in participating in the study or want to learn more, please get in touch. Contact us
This study is no longer recruiting.

Description

The purpose of this study is to determine the safety and tolerability of an experimental form of therapy, known as WU-CART-007 ("study drug"). WU-CART-007 uses immune cells, called T cells, that are genetically changed to identify cancer cells. In this study, T cells are collected from a healthy human donor and have been modified in a laboratory. If the genetically changed T cells recognize and attach to cancer cells, they may have the ability to kill those cancer cells.

Patients with T-cell Acute Lymphoblatic Leukemia (T-ALL) or Lymphoblastic Lymphoma (LBL), where the disease has come back (relapsed) or has not responded to treatment (refractory) may be eligible for the study.


Eligibility and criteria


IRB Number:
21-019423
Eligible age range:
12 years - 30 years
Clinical trial phase:
Phase I
Phase II
Official title:
A Phase 1/2 Dose-Escalation and Dose-Expansion Study of the Safety and Efficacy of Anti-CD7 Allogeneic CAR-T cells (WU-CART-007) in Patients with Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia (T-ALL)/Lymphoblastic Lymphoma (LBL)

What to expect


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