Judith R. Kelsen, MD
Areas of expertise: Inflammatory bowel disease (IBD), Very Early-onset inflammatory bowel disease
Locations: Main Building
About Judith R. Kelsen, MD
Titles
Attending Physician
Associate Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Certifications
Gastroenterology – American Board of Internal Medicine
Pediatrics – American Board of Pediatrics
Awards and Honors
2023, Academy of Master Clinicians, University of Pennsylvania
2022, Philadelphia Magazine's Top Doctors in Gastroenterology, Hepatology and Nutrition
2014, Young Faculty Investigator Award, The North American Society for Gastroenterology, Hepatology and Nutrition
2009, Komarov Research Competition, Clinical Sciences, 3rd place
2009, We Care Digestive Disease Week Travel Grant
2008, North American Society for Pediatric Gastroenterology Hepatology, and Nutrition Travel Grant
Leadership and Memberships
Memberships in professional organizations
International
2018-present, International Inflammatory Bowel Disease Genetics Consortium
2006-present, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition
- 2015, IBD Committee
- 2012, Professional Education Committee
National
2015-present, Improved Care Now Network
2010-present, The Crohn's and Colitis Foundation of America
2006-present, American Gastroenterological Association (AGA)
2006-present, American Association for the Study of Liver Diseases (AASLD)
2001-present, American Academy of Pediatrics (AAP)
Editorial and Academic Positions
Editorial positions
2013-present, JPGN, Ad Hoc reviewer
2012-present, PLOS ONE, Ad Hoc reviewer
2009-present, American Journal of Gastroenterology, Ad Hoc Reviewer
2008-present, Inflammatory Bowel Diseases, Ad Hoc Reviewer
Academic and institutional committees
2016-present, CHOP Antibiotics DUE subcommittee
2016-present, Clinic Trials Workgroup
2014-present, CHOP Therapeutics and Standards Committee
Education & training
Graduate Degree
MTR - University of Pennsylvania, Philadelphia, PA
Medical Degree
MD - The Weill Medical School of Cornell University, New York, NY
Internship
Pediatrics - Albert Einstein Medical Center, Philadelphia, PA
Residency
Pediatrics - Mount Sinai Medical Center, New York, NY
Fellowship
Pediatric Gastroenterology, Hepatology and Nutrition - The Children's Hospital of Philadelphia, Philadelphia, PA (Chief Fellow)
IBD Clinical Research Fellowship - Center for Pediatric Inflammatory Bowel Disease, The Children's Hospital of Philadelphia, Philadelphia, PA
Master of Translational Research - The University of Pennsylvania, Philadelphia, PA
Additional Training
Certificate in Epidemiology and Biostatistics - University of Pennsylvania, Philadelphia, PA
Publications
Publications
2023
Whaley KG, Xiong Y, Karns R, Hyams JS, Kugathasan S, Boyle BM, Walters TD, Kelsen J, LeLeiko N, Shapiro J, Waddell A, Fox S, Bezold R, Bruns S, Widing R, Haberman Y, Collins MH, Mizuno T, Minar P, D'Haens GR, Denson LA, Vinks AA, Rosen MJ.: Multicenter Cohort Study of Infliximab Pharmacokinetics and Therapy Response in Pediatric Acute Severe Ulcerative Colitis. Clin Gastroenterol Hepatol May 2023.
2022
Oxana Dmitrieva-Posocco 1, Andrea C Wong 1, Patrick Lundgren 1, Aleksandra M Golos 1, Hélène C Descamps 1, Lenka Dohnalová 1, Zvi Cramer 2, Yuhua Tian 2, Brian Yueh 3, Onur Eskiocak 3, Gabor Egervari 4, Yemin Lan 4, Jinping Liu 5 6, Jiaxin Fan 7, Jihee Kim 1, Bhoomi Madhu 1, Kai Markus Schneider 1, Svetlana Khoziainova 1 8 9 10, Natalia Andreeva 8 9 10, Qiaohong Wang 4 11, Ning Li 2, Emma E Furth 12, Will Bailis 13, Judith R Kelsen 14, Kathryn E Hamilton 14, Klaus H Kaestner 5 6, Shelley L Berger 4, Jonathan A Epstein 4 11, Rajan Jain 4 11, Mingyao Li 7, Semir Beyaz 3, Christopher J Lengner 2, Bryson W Katona 15, Sergei I Grivennikov 8 9 10, Christoph A Thaiss 16 17 18, Maayan Levy 19 20: β-Hydroxybutyrate suppresses colorectal cancer. Nature May 2022.
Basavaraj Kerur 1, Karoline Fiedler 2, Marisa Stahl 3, Jeffrey Hyams 4, Michael Stephens 5, Ying Lu 6, Marian Pfefferkorn 7, Raza Alkhouri 8, Jennifer Strople 9, Judith Kelsen 10, Leah Siebold 11, Alka Goyal 12, Joel R Rosh 13, Neal LeLeiko 14, Johan Van Limbergen 15, Anthony L Guerrerio 16, Ross M Maltz 17, Lina Karam 18, Eileen Crowley 19, Anne M Griffiths 2, Melvin B Heyman 20, Mark Deneau 21, Keith Benkov 22, Joshua Noe 23, Dedrick Moulton 24, Helen Pappa 25, Joseph Galanko 26, Scott Snapper 27, Aleixo M Muise 2, Michael D Kappelman 26, Eric I Benchimol 28 2: Utilization of Antitumor Necrosis Factor Biologics in Very Early Onset Inflammatory Bowel Disease: A Multicenter Retrospective Cohort Study From North America. J pediatr Gastro Nutr July 2022.
Aleksejs Sazonovs # 1, Christine R Stevens # 2 3 4, Guhan R Venkataraman # 5, Kai Yuan # 3 4, Brandon Avila 2, Maria T Abreu 6, Tariq Ahmad 7, Matthieu Allez 8, Ashwin N Ananthakrishnan 9, Gil Atzmon 10 11, Aris Baras 12, Jeffrey C Barrett 13, Nir Barzilai 11 14, Laurent Beaugerie 15, Ashley Beecham 16 17, Charles N Bernstein 18, Alain Bitton 19, Bernd Bokemeyer 20, Andrew Chan 21 22, Daniel Chung 23, Isabelle Cleynen 24, Jacques Cosnes 25, David J Cutler 26 27, Allan Daly 28, Oriana M Damas 29, Lisa W Datta 30, Noor Dawany 31, Marcella Devoto 31 32 33 34, Sheila Dodge 35, Eva Ellinghaus 36, Laura Fachal 1, Martti Farkkila 37, William Faubion 38, Manuel Ferreira 12, Denis Franchimont 39, Stacey B Gabriel 35, Tian Ge 3 40 41, Michel Georges 42, Kyle Gettler 43, Mamta Giri 43, Benjamin Glaser 44, Siegfried Goerg 45, Philippe Goyette 46, Daniel Graham 47 48 49, Eija Hämäläinen 50, Talin Haritunians 51, Graham A Heap 7, Mikko Hiltunen 52, Marc Hoeppner 53, Julie E Horowitz 12, Peter Irving 54 55, Vivek Iyer 28, Chaim Jalas 56, Judith Kelsen 31, Hamed Khalili 21, Barbara S Kirschner 57, Kimmo Kontula 58, Jukka T Koskela 50, Subra Kugathasan 27, Juozas Kupcinskas 59, Christopher A Lamb 60 61, Matthias Laudes 45, Chloé Lévesque 46, Adam P Levine 62, James D Lewis 34 63, Claire Liefferinckx 39, Britt-Sabina Loescher 36, Edouard Louis 42, John Mansfield 60 61, Sandra May 36, Jacob L McCauley 16 17, Emebet Mengesha 51, Myriam Mni 42, Paul Moayyedi 64, Christopher J Moran 23, Rodney D Newberry 65, Sirimon O'Charoen 63, David T Okou 27 66, Bas Oldenburg 67, Harry Ostrer 68, Aarno Palotie 2 3 4 50 69 70, Jean Paquette 46, Joel Pekow 57, Inga Peter 43, Marieke J Pierik 71, Cyriel Y Ponsioen 72, Nikolas Pontikos 62, Natalie Prescott 73, Ann E Pulver 74, Souad Rahmouni 42, Daniel L Rice 1, Päivi Saavalainen 75, Bruce Sands 43, R Balfour Sartor 76, Elena R Schiff 62, Stefan Schreiber 36, L Philip Schumm 77, Anthony W Segal 62, Philippe Seksik 15, Rasha Shawky 78, Shehzad Z Sheikh 76, Mark S Silverberg 79, Alison Simmons 80, Jurgita Skeiceviciene 59, Harry Sokol 15, Matthew Solomonson 2, Hari Somineni 81, Dylan Sun 12, Stephan Targan 51, Dan Turner 82, Holm H Uhlig 83 84, Andrea E van der Meulen 85, Séverine Vermeire 86 87, Sare Verstockt 87, Michiel D Voskuil 88, Harland S Winter 23, Justine Young 63; Belgium IBD Consortium; Cedars-Sinai IBD; International IBD Genetics Consortium; NIDDK IBD Genetics Consortium; NIHR IBD BioResource; Regeneron Genetics Center; SHARE Consortium; SPARC IBD Network; UK IBD Genetics Consortium; Richard H Duerr 89, Andre Franke 36, Steven R Brant 30 90, Judy Cho 43, Rinse K Weersma 88, Miles Parkes 91, Ramnik J Xavier 47 48 49 92 93 94 95 96, Manuel A Rivas 5, John D Rioux 46 97, Dermot P B McGovern 51, Hailiang Huang 98 99, Carl A Anderson 100, Mark J Daly 101: Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility. Nat Gen September 2022.
Eliana Shaul 1, Máire A Conrad 1 2, Noor Dawany 3, Trusha Patel 1 2, Megan C Canavan 1, Alyssa Baccarella 1, Sarah Weinbrom 1, Daniel Aleynick 1, Kathleen E Sullivan 2 4, Judith R Kelsen 1 2: Canakinumab for the treatment of autoinflammatory very early onset- inflammatory bowel disease. Front Immunol September 2022.
Judith Kelsen 1, Noor Dawany 2, Maire Conrad 1, Trusha Patel 1, Marcella Devoto 3, Kelly Maurer , Kathleen E Sullivan : Clinical and laboratory predictors of monogenic very early onset inflammatory bowel disease. Clin Immunol 2022.
2021
30. Maribeth R Nicholson, Suchitra K Hourigan, Maire Conrad, Alka Goyal, Kyle Jensen, Judith Kelsen, Melissa Kennedy, Madison Weatherly, Stacy A Kahn: Current Challenges in Fecal Microbiota Transplantation for Clostridioides difficile Infection in Children. Am J Gastroenterol June 2021.
Christina E Holbein, Jill Plevinsky, Trusha Patel, Maire C Conrad, Judith R Kelsen: Pediatric Global Health in Children with Very Early-Onset Inflammatory Bowel Disease. J Peds Psychol July 2021.
Trusha Patel MD, Sarah E. Henrickson MD PhD, Emily Moser PhD, Natania S. Field, Kelly Maurer, Noor Dawany PhD, Maire Conrad MD MS, Nancy Bunin MD, Jason Freedman MD MSCE, Jennifer Heimall MD, Danielle E. Arnold MD, Jing Wang MD ABMGG FACMG4, Jonathan E. Markowitz MD, Sarah Beth Payne-Poff MD, Kelli W. Williams MD MPH, Pierre A. Russo MD, John Wherry PhD, Marcella Devoto PhD, Paula Oliver PhD, Kathleen E. Sullivan MD PhD, and Judith R. Kelsen MD: Immune dysregulation in human ITCH deficiency successfully treated with hematopoietic cell transplantation. JACI July 2021.
Sharmistha Rudra, Eliana Shaul, Maire Conrad, Trusha Patel, Astrela Moore, Noor Dawany, Megan Canavan, Kathleen E. Sullivan, Edward Behrens, Judith R. Kelsen: Ruxolitinib: Targeted Approach for Treatment of Autoinflammatory Very Early Onset-Inflammatory Bowel Disease. Clinical Gastro Hep August 2021.
Strigli A, Gopalakrishnan S, Zeissig Y, Basic M, Wang J, Schwerd T, Doms S, Peuker K, Hartwig J, Harder J, Hönscheid P, Arnold P, Kurth T, Rost F, Petersen BS, Forster M, Franke A, Kelsen JR, Rohlfs M, Klein C, Muise AM, Warner N, Nambu R, Mayerle J, Török HP, Linkermann A, Muders MH, Baretton GB, Hampe J, Aust DE, Baines JF, Bleich A, Zeissig S.: Deficiency in X-linked inhibitor of apoptosis protein promotes susceptibility to microbial triggers of intestinal inflammation. Sci Immunology November 2021.
Dou Y, Maurer K, Patel T, Conrad M, Shraim R, Sullivan K, Kelsen JR: Mucosal Invariant T cells are Diminished in Very Early-Onset Inflammatory Bowel Disease. JPGN 2021.
Hua-Hsi Hung, Hung-Chang Lee , Chun-Yan Yeung , Nien-Lu Wang, Tzu-Yin Tang, Harland S Winter, Judith R Kelsen , Chuen-Bin Jiang : Importance of early detection of infantile inflammatory bowel disease with defective IL-10 pathway: A case report. Case Reports 2021.
Jodie Ouahed*, Judith R. Kelsen*, Waldo A. Spessott, Kameron Kooshesh, Maria L. Sanmillan, Noor Dawany, Kathleen E. Sullivan, Kathryn Hamilton, Voytek Slowik, Sergey Nejentsev, João Farela Neves, Helena Flores, Wendy K. Chung, Ashley Wilson, Kwame Anyane Yeboa, Karen Wou, Preti Jain, Michael Field, Sophia Tollefson, Maiah H. Dent, Dalin Li1, Takeo Naito15, Dermot P.B. McGovern15, Andrew Kwong16, Faith Talliaferro1,17, Jose-Ordonas Montanes1, 17, 18, 19, Bruce Horwitz 1, Daniel Kotlarz1, Christoph Klein, Jonathan Evans, Neil Warner, Abdul Elkadri, Aleixo M. Muise, Jeffrey Goldsmith, Benjamin Thompson, Karin R. Engelhardt, Andrew J. Cant, Sophie Hambleton, Andrew Barclay, Agnes Toth-Petroczy, Dana Vuzman, Nikkola Carmichael, Corneliu Bodea, Christopher A. Cassa, Marcella Devoto, Richard L. Maas, Edward M. Behrens, Claudio G. Giraudo, and Scott B. Snapper, : Variants in STXBP3 is Associated with Very Early Onset Inflammatory Bowel Disease, Bilateral Sensorineural Hearing Loss and Immune Dysregulation. Journal of Crohn's and Colitis 2021.
Maribeth R Nicholson 1, Erin Alexander 2, Sonia Ballal 3, Zev Davidovics 4, Michael Docktor 3, Michael Dole 1, Jonathan M Gisser 5, Alka Goyal 6, Suchitra K Hourigan 7, M Kyle Jensen 8, Jess L Kaplan 9, Richard Kellermayer 10, Judith R Kelsen 11, Melissa A Kennedy 11, Sahil Khanna 2, Elizabeth D Knackstedt 8, Jennifer Lentine 12, Jeffery D Lewis 13, Sonia Michail 14, Paul D Mitchell 3, Maria Oliva-Hemker 15, Tiffany Patton 16, Karen Queliza 10, Sarah Sidhu 15, Aliza B Solomon 12, David L Suskind 17, Madison Weatherly 3, Steven Werlin 18, Edwin F de Zoeten 19, Stacy A Kahn 3, North American Society of Pediatric Gastroenterology and Nutrition Fecal Microbiota Transplantation Special Interest Group: Efficacy and Outcomes of Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection in Children with Inflammatory Bowel Disease. JCC 2021.
2020
Nicholson MR, Mitchell PD, Alexander E, Ballal S, Bartlett M, Becker P, Davidovics Z, Docktor M, Dole M, Felix G, Gisser J, Hourigan SK, Jensen MK, Kaplan JL, Kelsen J, Kennedy M, Khanna S, Knackstedt E, Leier M, Lewis J, Lodarek A, Michail S, Oliva-Hemker M, Patton T, Queliza K, Russell GH, Singh N, Solomon A, Suskind DL, Werlin S, Kellermayer R, Kahn SA: Efficacy of Fecal Microbiota Transplantation for Clostridium difficile Infection in Children. Clin Gastroenterol Hepatol 18(3): 612-619, March 2020.
Kelsen JR, Conrad MA, Dawany N, Patel T, Shraim R, Merz A, Maurer K, Sullivan KE, Devoto M.: The Unique Disease Course of Children with Very Early onset-Inflammatory Bowel Disease. Inflammatory Bowel Disease 26(6): 909-918, May 2020.
Kerur B, Benchimol EI, Fiedler K, Stahl M, Hyams J, Stephens M, Lu Y, Pfefferkorn M, Alkhouri R, Strople J, Kelsen J, Siebold L, Goyal A, Rosh JR, LeLeiko N, Van Limbergen J, Guerrerio AL, Maltz R, Karam L, Crowley E, Griffiths A, Heyman MB, Deneau M, Benkov K, Noe J, Mouton D, Pappa H, Galanko JA, Snapper S, Muise AM, Kappelman MD: Natural History of  Very Early Onset Inflammatory Bowel Disease in North America: A Retrospective Cohort Study. Inflamm Bowel Dis Page: doi: 10.1093, May 2020 Notes: epub ahead of print.
Liang G, Conrad MA, Kelsen JR, Kessler LR, Breton J, Albenberg LG, Marakos S, Galgano A, Devas N, Erlichman J, Zhang H, Mattei L, Bittinger K, Baldassano RN, Bushman FD: The dynamics of the stool virome in very early onset inflammatory bowel disease. J Crohns Colitis Page: doi: 10.1093, May 2020 Notes: epub ahead of print.
Kelsen JR, Dawany N, Conrad MA, Karakasheva TA, Maurer K, Wei JM, Uman S, Dent MH, Behera R, Bryant LM, Ma X, Moreira L, Chatterji P, Shraim R, Merz A, Mizuno R, Simon LA, Muir AB, Giraudo C, Behrens EM, Whelan KA, Devoto M, Russo PA, Andres SF, Sullivan KE, Hamilton KE.: Colonoids From Patients With Pediatric Inflammatory Bowel Disease Exhibit Decreased Growth Associated With Inflammation Severity and Durable Upregulation of Antigen Presentation Genes. Inflamm Bowel Dis Page: doi: 10.1093, June 2020 Notes: epub ahead of print.
Frederic D Bushman , Maire Conrad , Yue Ren , Chunyu Zha , Christopher Gu , Christopher Petucci , Min-Soo Kim , Arwa Abbas , Kevin J Downes , Nina Devas , Lisa M Mattei , Jessica Breton , Judith Kelsen , Sarah Marakos , Alissa Galgano, Kelly Kachelries, Jessi Erlichman, Jessica L Hart , Michael Moraskie, Dorothy Kim , Huanjia Zhang, Casey E Hofstaedter, Gary D Wu , James D Lewis , Joseph P Zackular , Hongzhe Li, Kyle Bittinger, Robert Baldassano : Multi-omic Analysis of the Interaction between Clostridioides difficile Infection and Pediatric Inflammatory Bowel Disease. Cell Host Microbe September 2020.
2019
Breton J, Kastl A, Hoffmann N, Rogers R, Grossman AB, Mamula P, Kelsen JR, Baldassano RN, Albenberg L.: Efficacy of Combination Antibiotic Therapy for Refractory Pediatric Inflammatory Bowel Disease. IBD Feb 2019.
Taylor DM, Aronow BJ, Tan K, Bernt K, Salomonis N, Greene CS, Frolova A, Henrickson SE, Wells A, Pei L, Jaiswal JK, Whitsett J, Hamilton KE, MacParland SA, Kelsen J, Heuckeroth RO, Potter SS, Vella LA, Terry NA, Ghanem LR, Kennedy BC, Helbig I, Sullivan KE, Castelo-Soccio L, Kreigstein A, Herse F, Nawijn MC, Koppelman GH, Haendel M, Harris NL, Rokita JL, Zhang Y, Regev A, Rozenblatt-Rosen O, Rood JE, Tickle TL, Vento-Tormo R, Alimohamed S, Lek M, Mar JC, Loomes KM, Barrett DM, Uapinyoying P, Beggs AH, Agrawal PB, Chen YW, Muir AB, Garmire LX, Snapper SB, Nazarian J, Seeholzer SH, Fazelinia H, Singh LN, Faryabi RB, Raman P, Dawany N, Xie HM, Devkota B, Diskin SJ, Anderson SA, Rappaport EF, Peranteau W, Wikenheiser-Brokamp KA, Teichmann S, Wallace D, Peng T, Ding YY, Kim MS, Xing Y, Kong SW, Bönnemann CG, Mandl KD, White PS: The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. Dev Cell March 2019.
Conrad MA, Carreon CK, Dawany N, Russo P, Kelsen JR: Distinct histopathological features at diagnosis of very early onset inflammatory bowel disease. J Crohns and Colitis April 2019.
Fernandez IZ, Baxter RM, Garcia-Perez JE, Vendrame E, Ranganath T, Kong DS, Lundquist K, Nguyen T, Ogolla S, Black J, Galambos C, Gumbart JC, Dawany N, Kelsen JR, de Zoeten EF, Quinones R, Eissa H, Verneris MR, Sullivan KE, Rochford R, Blish CA, Kedl RM, Dutmer CM, Hsieh EWY.: A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation. J Exp Med April 2019.
Nicholson MR, Mitchell PD, Alexander E, Ballal S, Bartlett M, Becker P, Davidovics Z, Docktor M, Dole M, Felix G, Gisser J, Hourigan SK, Jensen MK, Kaplan JL, Kelsen J, Kennedy M, Khanna S, Knackstedt E, Leier M, Lewis J, Lodarek A, Michail S, Oliva-Hemker M, Patton T, Queliza K, Russell GH, Singh N, Solomon A, Suskind DL, Werlin S, Kellermayer R, Kahn SA: Efficacy of Fecal Microbiota Transplantation for Clostridium difficile Infection in Children. Clin Gastroenterol Hepatol April 2019.
Zhou L, Chu C, Teng F, Bessman NJ, Goc J, Santosa EK, Putzel GG, Kabata H, Kelsen JR, Baldassano RN, Shah MA, Sockolow RE, Vivier E, Eberl G, Smith KA, Sonnenberg GF.: Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2. Nature April 2019.
Kelsen JR, Conrad MA, Dawany N, Patel T, Shraim R, Merz A, Maurer K, Sullivan KE, Devoto M.: The Unique Disease Course of Children with Very Early onset-Inflammatory Bowel Disease. Inflammatory Bowel Disease September 2019.
2018
O'Connell AE, Zhou F, Shah MS, Murphy Q, Rickner H, Kelsen J, Boyle J, Doyle JJ, Gangwani B, Thiagarajah JR, Kamin DS, Goldsmith JD, Richmond C, Breault DT, Agrawal PB.: Neonatal-Onset Chronic Diarrhea Caused by Homozygous Nonsense WNT2B Mutations. Am J Hum Genet. 103(1): 131-137, July 2018.
Clarke EL, Connell AJ, Six E, Kadry NA, Abbas AA, Hwang Y, Everett JK, Hofstaedter CE, Marsh R, Armant M, Kelsen J, Notarangelo LD, Collman RG, Hacein-Bey-Abina S, Kohn DB, Cavazzana M, Fischer A, Williams DA, Pai SY, Bushman FD.: T cell dynamics and response of the microbiota after gene therapy to treat X-linked severe combined immunodeficiency. Genome Medicine 10, September 2018.
Dunn K, Pasternak B, Kelsen JR, Sullivan KE, Dawany N, Wright BL.: Mevalonate kinase deficiency presenting as recurrent rectal abscesses and perianal fistulae. Ann Allergy Asthma Immunol 2018.
Mao L, Kitani A, Similuk M ,Oler AJ, Albenberg L , Kelsen J, Aktay A, Quezado M, Yao M, Montgomery-Recht K, Fuss IJ, Strober W: Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease. J Clin Invest 2018.
2017
Canna SW, Girard C, Malle L, de Jesus A, Romberg N, Kelsen J, Surrey LF, Russo P, Sleight A, Schiffrin E, Gabay C, Goldbach-Mansky R, Behrens EM: Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition. J. Allergy Clin Immunol. 139(5): 1698-1701, May 2017.
Schwerd T, Bryant RV, Pandey S, Capitani M, Meran L, Cazier JB, Jung J, Mondal K, Parkes M, Mathew CG, Fiedler K, McCarthy DJ; WGS500 Consortium; Oxford IBD cohort study investigators; COLORS in IBD group investigators; UK IBD Genetics Consortium, Sullivan PB, Rodrigues A, Travis SPL, Moore C, Sambrook J, Ouwehand WH, Roberts DJ, Danesh J; INTERVAL Study, Russell RK, Wilson DC, Kelsen JR, Cornall R, Denson LA, Kugathasan S, Knaus UG, Serra EG, Anderson CA, Duerr RH, McGovern DP, Cho J, Powrie F, Li VS, Muise AM, Uhlig HH.: NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease. Mucosal Immunology Page: doi: 10.1038, November 2017 Notes: Epub ahead of print.
Máire A. Conrad MD, MS1,2*, Noor Dawany PhD3, Kathleen E. Sullivan MD, PhD2,4, Marcella Devoto PhD2,5,6,7, Judith R. Kelsen MD1,2 : Novel ZBTB24 mutation associated with immunodeficiency, centromere instability, and facial anomalies type 2 syndrome identified in a patient with very early onset inflammatory bowel disease. Inflammatory Bowel Disease 23(12): 2252-2255, December 2017.
Maxwell E, Dawany N, Baldassano RN, _ Mamula P, Mattei P, Albenberg L, Kelsen JR: Diverting Ileostomy for the Treatment of Severe, Refractory, Pediatric Inflammatory Bowel Disease. JPGN January 2017.
2016
Zhe Zhang, Ph.D.; Lihua Shi, Ph.D.; Noor Dawany; Judith Kelsen; Michelle A Petri, MD MPH; Kathleen E Sullivan, MD PHD: H3K4 tri-methylation breadth at transcription start sites impacts the transcriptome of systemic lupus erythematosus. Clinical Epigenetics 2016.
Canna SW, Girard C, Malle L, de Jesus A, Romberg N, Kelsen J, Surrey LF, Russo P, Sleight A, Schiffrin E, Gabay C, Goldbach-Mansky R, Behrens EM: Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition. J. Allergy Clin Immunol. November 2016.
Conrad MA1, Stein RE, Maxwell EC, Albenberg L, Baldassano RN, Dawany N, Grossman AB, Mamula P, Piccoli DA, Kelsen JR.: Vedolizumab Therapy in Severe Pediatric Inflammatory Bowel Disease. Inflamm Bowel Dis October 2016.
Rosenbaum DG, Conrad MA, Biko DM, Ruchelli ED, Kelsen JR, Anupindi SA: Ultrasound and MRI predictors of surgical bowel resection in pediatric Crohn disease. Pediatr Radiol September 2016.
Rona Yaeger, Manish A. Shah, Vincent A. Miller, Judith R. Kelsen, Kai Wang, Zachary J. Heins, Jeffrey S. Ross, Yuting He, Eric Sanford, Rhonda K. Yantiss, Sohail Balasubramanian, Philip J. Stephens, Nikolaus Schultz, Moshe Oren, Laura Tang, David Kelsen: Genomic Alterations Observed in Colitis-associated Cancers are Distinct from Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease. Gastroenterology April 2016.
David R. Withers*, Matthew R. Hepworth, Xinxin Wang, Emma C. Mackley, Emily E. Halford, Emma E. Dutton, Clare L. Marriott, Verena Brucklacher-Waldert, Marc Veldhoen, Judith Kelsen, Robert N. Baldassano, Gregory F. Sonnenberg : Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving ILC3 Nature Medicine January 2016.
2015
Sahn B, Chen-Lim ML, Ciavardone D, Farace L, Jannelli F, Nieberle M, Ely E, Zhang X, Kelsen J, Puma A, Mamula P.: Safety of a 1-Day Polyethylene Glycol 3350 Bowel Preparation for Colonoscopy in Children. JPGN 2015.
Kelsen J, Bittinger K, Pauly-Hubabrd H, Posivak L, Grunberg S, Baldassano R, Lewis J, Wu G, Bushman F: Alterations of the Subgingival microbiota in pediatric Crohn's Disease Studied longitudinally in Discovery and Validation cohorts. Inflammatory Bowel Disease 21(12), December 2015.
Judith R. Kelsen, Noor Dawany, Christopher J. Moran, Mahdi Sarmady, Ariella Sasson, Helen Pauly-Hubbard, Alejuandro Martinez, Kelly Maurer, Joanne Soong Eric Rappaport, Harland S. Winter, Petar Mamula, David A. Piccoli, Mark Daly, David Artis, Gregory F. Sonnenberg, Kathleen E. Sullivan, Robert N. Baldassano, Marcella Devoto: Exome Sequencing Analysis Reveals variants in Primary Immunodeficiency Genes in Very Early Onset Inflammatory Bowel Disease. Gastroenterology 149(6): 1415-24, Nov 2015.
Judith R. Kelsen, MD1, Noor Dawany, PhD,2 Alejuandro Martinez,1 Christopher M. Grochowski,3 Kelly Maurer, 4 Eric Rappaport, PhD5, David A. Piccoli, MD1 Robert N. Baldassano, MD1, Petar Mamula, MD1, Kathleen E. Sullivan, MD, PhD4, Marcella Devoto, PhD6: A de novo whole gene deletion of XIAP Detected by Exome Sequencing Analysis in Very Early Onset Inflammatory Bowel Disease. BMC Gastroenterol 15, November 2015.
Hepworth, Mauser, Kelsen, Baldassano, Sonnenberg: Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD+4 T cells." Science April 2015.
Sahn B, Anupindi SA, Dadhania NJ, Kelsen JR, Nancy ML, Mamula P: Duodenal Hematoma Following EGD: Comparison with Blunt Abdominal Trauma-Induced Duodenal Hematoma. JPGN 60(1), Jan 2015.
2013
Gupta K, Noble A, Kachelries KE, Albenberg L, Kelsen JR, Grossman AB, Baldassano RN: A novel enteral nutrition protocol for the treatment of pediatric Crohn's disease. Inflamm Bowel Dis 19(7): 1374-8, June 2013.
Christopher J. Cardinale, Judith R. Kelsen, Robert N. Baldassano, and Hakon Hakonarson: The Impact of Exome Sequencing in Inflammatory Bowel Disease. World Journal of Gastroenterology In press 2013.
2012
Judith Kelsen, Gary Wu: The gut microbiota, environment and diseases of modern society Gut Microbes. Landes Bioscience, 3(4), July 2012 Notes: Epub ahead of print.
Lindsey Albenberg, Petar Mamula, Judith Kelsen: Biologics for the treatment of moderate-severe ulcerative colitis in pediatric patients. Pediatric Health, Medicine and Therapeutics. Dove Press, In print, 2012.
2011
Dige A, Hvas CL, Deleuran B, Kelsen J, Bendix-Stuve M, Dahlerup JF, et al. Adalimumab treatment in Crohn's disease does not induce early changes in regulatory T cells. Scand J Gastroenterol. 2011 Oct;46(10):1206-14. Epub 2011 July 27. Cited in PubMed; PMID 21793633.
Kelsen J, Dige A, Schwindt H, D'Amore F, Pedersen FS, Agnholt J, et al. Infliximab induces clonal expansion of yδ-T cells in Crohn's disease: a predictor of lymphoma risk: PLoS One. 2011 Mar 31;6(3):e17890. Cited in PubMed; PMID 21483853.
Kelsen JR, Kim J, Latta D, Smathers S, McGowan KL, Zaoutis T, et al. Recurrence rate of clostridium difficile infection in hospitalized pediatric patients with inflammatory bowel disease. Inflamm Bowel Dis. 2011 Jan;17(1):50-5. Doi: 10.1002/ibd.21421. Epub 2010 Aug 18. Cited in PubMed; PMID 20722068.
Jørgensen SP, Agnholt J, Glerup H, Lyhne S, Villadsen GE, Hvas CL, et al. Clinical trial: vitamin D3 treatment in Crohn's disease - a randomized double-blind placebo-controlled study. Aliment Pharmacol Ther. 2010 Aug;32(3):377-83. Epub 2010 may 11. Cited in PubMed; PMID 20491740.
2010
Kelsen JR, Rosh J, Heyman M, Winter HS, Ferry G, Cohen S, et al. Phase I trial of sargramostim in pediatric Crohn's disease. Inflamm Bowel Dis. 2010 Jul;16(7):1203-8. Epub 2010 Jan 5. Cited in PubMed; PMID 20052780.
Books
Mamula, Grossman, Baldassano, Kelsen, Markowitz: Pediatric Inflammatory Bowel Disease, Volume 3. Springer. Mamula, Grossman, Baldassano, Kelsen, Markowitz (eds.). 3, June 2017.
Editorials, Reviews, Chapters
2015
Dulik M, Slack I, Kelsen J, Spinner N: Genetic and Metabolic Disorders, Genetic Testing. Walker's Pediatric Gastrointestinal Disease. Kleiman, Goulet, Meili-Vergani, Sanderson, Sherman, Schneider (eds.). Page: Chapter 34, 2015 Notes: 6th edition.
2012
Menard C, Kelsen J: Perianal Abscess in Children. The 5-Minute Pediatric Consult. LWW, 6, 2012.
Kelsen J, Markowitz J: Ulcerative Colitis in Children. The 5-Minute Pediatric Consult. LWW, 6, 2012.
Judith Kelsen, Maria Mascarenhas: Upper Gastrointestinal Bleeding. Five Minute Pediatric Consult. Schwartz, Bell, Bingham, Friedman, Loomes, Mamula, Mascarenhas, Tanel (eds.). LWW, 6: 886-887, 2012.
Judith Kelsen, Gary Wu: The Gut Microbiota and IBD. Pediatric Inflammatory Bowel Disease. Mamula, Baldassano, Markowitz (eds.). Springer, 2, In print 2012.
Judith Kelsen, Andrew Mulberg: Imperforate Anus. Five Minute Pediatric Consult. Schwartz, Bell, Bingham, Friedman, Loomes, Mamula, Mascarenhas, Tanel (eds.). LWW, 6, 2012.
Albenberg L, Mamula P, Kelsen J: Biologics for the treatment of moderate to severe ulcerative colitis in pediatric patients. Pediatric Health, Medicine and Therapeutics 3: 51-8, 2012.
Albenberg L, Kelsen J, Baldassano RN: Pediatric Considerations in Medical Therapy in Patients with ulcerative colitis, The Complete Guide to Medical Management. Medical Therapy of ulcerative colitis. Gary Lichenstein (eds.). Springer, 2, In print 2012.
2011
Lindsey Albenberg, Judith Kelsen, Robert Baldassano: Pediatric Considerations in Medical Therapy in Patients with Crohn's Disease, The Complete Guide to Medical Management. Medical therapy for Crohn's Disease. Lichenstein (eds.). Springer, 3, 2011.
Kelsen J, Hunter A, Baldessano RN: Pediatric therapies in inflammatory bowel disease. Advanced Therapy in Inflammatory Bowel Disease. Theodore M. Bayless and Stephen B. Hanauer (eds.). People's Medical Publishing House, 1, 2011.
Kelsen J, Baldassano RN, : Pediatric Considerations in Medical Therapy in Patients with Ulcerative Colitis. Medical Therapy in Patients with Ulcerative Colitis, The Complete Guide to Medical Management. Gary Lichenstein (eds.). 2, 2011.
Anna Hunter, Judith Kelsen, Robert Baldassano: Crohn's disease therapy in Children and Adolescent. Advanced Therapies In Inflammatory Bowel Disease. Theodore M. Bayless (eds.). 3, 2011.
Kelsen J, Mamula P: Ulcerative Colitis in Children. eMedicine from WebMD March 2011.
2010
Anupindi S, Ayyala R, Kelsen J, Mamula P, Applegate K: Imaging of inflammatory bowel disease in children. Evidence-Based Imaging in Pediatrics. Medine, Appelgate, Blackmore (eds.). Springer Page: 487-505, 2010.
2008
Kelsen J, Mascarenhas M. Upper gastrointestinal bleeding, In: Schwartz MW, editor. The 5-minute pediatric consult. Philadelphia: Lippincott, Williams and Wilkins; 2008. p. 886-887.
Kelsen J, Mulberg A. Imperforate anus. In: Schwartz MW, editor. The 5-minute pediatric consult. Philadelphia: Lippincott, Williams and Wilkins; 2008. p. 444-445.
Kelsen J, Mulberg A. C1 esterase inhibitor. In: Schwartz MW, editor. The 5-minute pediatric consult. Philadelphia: Lippincott, Williams and Wilkins; 2008.
Kelsen J, Mascarenhas M, Short bowel syndrome. In: Schwartz MW, editor. The 5-minute pediatric consult. Philadelphia: Lippincott, Williams and Wilkins; 2008. p. 774-775.