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Multidisciplinary Task Force Develops Clinical Recommendations for Rare, Life-Threatening Hyperinflammatory Syndromes
Hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) are overlapping hyperinflammatory syndromes that involve disorganization and malfunction of the immune system, leading to widespread inflammation and organ damage. The conditions can progress rapidly, making early identification and management key for preventing organ failure and death.
CHOP Researchers Show that IgA Fine Tunes the Body’s Interactions with Microbes
CHOP researchers have shown that IgA acts as a “tuner” that regulates the number of microbes the body sees every day, restraining a systemic immune response.
CHOP-led Study Identifies Two Different Regulatory T Cell Populations
A CHOP-led study has shown that a regulatory class of T cells descends from two different origins, one that relates to autoimmunity and one that relates to protective immunity.
CHOP Study Finds Safest Treatment for Immunodeficiency Disorder is Not Cost Effective for U.S. Patients
Using a model developed at CHOP, researchers find high cost of treatment most likely to prevent premature death in patients with agammaglobulinemia undermines its benefits.
Fewer Asthma Attacks During COVID Pandemic
After stay-at-home orders were issued, doctors at CHOP noticed a drop in the number of patients who were admitted for asthma emergencies.
Children’s Hospital of Philadelphia President and CEO Releases Special COVID-19 Podcast Series
Breaking Through with Madeline Bell’s “Where We Are Now” series highlights CHOP doctors and researchers who are working to bring an end to the COVID-19 pandemic.
How to Prevent Tick Bites
For families spending time outdoors this summer, ticks pose a big health risk. Find out how to best protect your family and what to do if your child is bitten.
CHOP-Pioneered Spatial Mapping Method Pinpoints Potential New Therapeutic Targets in Lupus
Findings could discover how disease-causing variations lead to a variety of autoimmune disorders.
Celebrating World PI Week
It's World PI Week! Join us in celebrating 10 years of collaboration, research and treatment for children with primary immunodeficiencies.
Partners In Preventing Eye Disease: Rheumatology And Ophthalmology
A 4-year-old boy presented to the emergency room reporting 2 weeks of right knee pain, swelling, and limping.