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Insights from the Gut Cell Atlas Convening 2024
The 2024 Gut Cell Atlas (GCA) Convening highlighted the most recent research advances into understanding the biology of Crohn’s disease. Drs. Kate Hamilton and Tatiana Karakasheva represent the Children’s Hospital of Philadelphia Research Institute in this initiative, which aims to build a detailed catalog the cell types composing human small and large intestines, further our understanding of Crohn's disease, and identify pathways towards curative therapy and ultimately, prevention.
2024 Research Annual Report, Did You Know: With Kathryn Hamilton, PhD, and Amanda Muir, MD
Doctors Amanda Muir and Kate Hamilton share a common interest in using patient-derived organoids to study pediatric gastrointestinal (GI) diseases. In 2019, they established the Gastrointestinal Epithelium Modeling Program, a collaborative effort dedicated to accelerating discovery and innovation in the search for cures and prevention strategies for these diseases.
Children’s Hospital of Philadelphia Researchers Characterize Spectrum of Causes and Symptoms of Mitochondrial DNA Deletion Rare Diseases
New techniques were utilized to recreate the goals of a natural history study of rare diseases in a fraction of the time.
Children’s Hospital of Philadelphia Researchers Develop Automated Tool for Integration and Analysis of Electronic Medical Record Data for Complex Rare Disease Patients
MMFP-Tableau offers a readily generalizable solution to make research and clinical electronic health system data more accessible and impactful.
The Signs and Symptoms of Gluten Sensitivity
Wondering if your child could be sensitive to gluten or benefit from a gluten-free diet? We asked Ritu Verma, MBChB, director of CHOP’s Center for Celiac Disease, for help in recognizing the signs of a gluten sensitivity.
Q&A with Binita M. Kamath, MBBChir, MRCP, MTR
CHOP’s new Chief of the Division of Gastroenterology, Hepatology and Nutrition shares her vision for the department’s future.
15th Annual Walk for Hope Raises More than $247,000 for CHOP’s Center for Pediatric Inflammatory Bowel Disease, Supporting Transformative Research and Care
Recently Children’s Hospital of Philadelphia (CHOP) hosted its annual Walk for Hope benefiting the Center for Pediatric Inflammatory Bowel Disease (IBD) at CHOP, raising more than $247,000 and sparking hope for a cure to IBD.
Children’s Hospital of Philadelphia Appoints New Chief of Gastroenterology, Hepatology and Nutrition
Children’s Hospital of Philadelphia (CHOP) has appointed Binita M. Kamath, MB BChir as Chief of the Division of Gastroenterology, Hepatology and Nutrition. Dr. Kamath has served for the last fifteen years as an attending physician in the Department of Gastroenterology, Hepatology and Nutrition at the Hospital for Sick Children (SickKids) in Ontario, Canada. She has been the interim Division Head at SickKids for the last 2 years.
CHOP Researchers Develop Method for Integrating Patient-Reported Outcomes for Patients with Primary Mitochondrial Disease
The findings also found that older patients with primary mitochondrial disease have a lower quality of life than pediatric patients with the same disease.
Web-Based Resource Provides Precise Classification of Dual Genome Variants of Primary Mitochondrial Disease
Quick-Mitome, developed by an international consortium of mitochondrial disease specialists, is available for non-commercial, non-clinical research.