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Researchers Publish Final Results of Key Clinical Trial for Gene Therapy for Sickle Cell Disease
In a landmark study, an international consortium led by researchers at CHOP published the final results of a key clinical trial of the gene therapy CASGEVY for the treatment of sickle cell disease.
International Team Led by CHOP Cancer Expert Receives Multimillion Dollar Grant for Childhood Cancer Research from Cancer Grand Challenges
Dr. Yael Mossé receives recognition for project dedicated to researching and potentially developing new therapies for undruggable solid tumors.
Esophageal and Airway Treatment (EAT) Program at CHOP
The Esophageal and Airway Treatment Program at CHOP specializes in treating children with airway and esophageal conditions.

CHOP Experts Showcase Frontier Program at Arab Health Exhibition
Showcasing its longstanding partnership with the United Arab Emirates Health Services, CHOP will exhibit thought-leading clinical research in the EHS booth at the Arab Health 2024 Exhibition and Congress in Dubai.
CHOP's John M. Maris MD, and Penn Medicine's E. John Wherry named 2024 Fellows of the AACR Academy
Distinguished pediatric oncologist John M. Maris, MD, has been named a member of the 2024 class of fellows of the American Association for Cancer Research (AACR) Academy. Each year, the AACR Academy recognizes and honors esteemed scientists whose major contributions have propelled significant innovation and progress against cancer.

FDA Approves Two Gene Therapies for Sickle Cell Disease
The Food and Drug Administration (FDA) has approved CASGEVY™ (exagamglogene autotemcel) and LYFGENIA™ (lovotibeglogene autotemcel), the first two gene therapies for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).
Children’s Hospital of Philadelphia Receives Multi-Million Dollar Gift from Holveck Family to Support Groundbreaking Osteosarcoma Research
Children’s Hospital of Philadelphia (CHOP) has received a $6.4 million gift from the family of Connor Boyle, a Central Bucks East High School graduate who died at age 18 from osteosarcoma. This three-year gift, named The Connor Initiative: Precision Therapeutics for Osteosarcoma & Rare Cancers, will support cutting-edge research in osteosarcoma and other rare cancers.
Dr. Yael Mossé and her team of global experts selected as finalists for the next Cancer Grand Challenges Awards
Dr. Mossé and her team, named KOODAC, will now compete for a chance to receive up to $25 million to tackle some of cancer's toughest challenges.
CHOP Establishes Kelly and Chad Punchard Endowed Chair in Translational Sarcoma Research
Children’s Hospital of Philadelphia (CHOP) has announced the establishment of the Punchard Family Endowed Chair in Translational Sarcoma Research. Patrick J. Grohar, MD, PhD, an attending physician with the Cancer Center and the Director of Translational Research with the Center for Childhood Cancer Research at CHOP, has been named the inaugural chair holder.
CHOP and Penn Researchers Find Behavioral Economics Strategies Can Help Patients Quit Smoking After a Cancer Diagnosis
“Nudges” from electronic health records could improve the implementation of tobacco use treatment almost three-fold over standard care.