CHOP researchers have developed a “dimmer switch” system based on alternative RNA splicing that can control levels of proteins expressed from gene therapy vectors.

Children’s Hospital of Philadelphia and the American Heart Association have announced an enhanced collaboration to advance the next generation of pediatric emergency cardiovascular care and resuscitation practices.

CHOP and Penn researchers have found an association between greenspace and improved mental health during the first six months of the pandemic.

CHOP researchers have developed a tool to screen children with food allergies for condition-related anxiety.

CHOP researchers have developed a novel method for producing new antibiotics to combat resistant bacteria, using a prodrug as a “Trojan horse” to mask the antibiotic.

CHOP researchers will use optical coherence tomography (OCT) to measure vision changes associated with NF1-related optic pathway gliomas.

In a proof-of-concept study, CHOP researchers used a vector to edit a single base mutation in Hurler Syndrome, halting progression of a disease that causes irreversible damage before birth.

CHOP researchers have found an association between child temperament and eating behaviors, including eating speed, responsiveness to the sight or smell of food, and satiety.

A drug discovered by CHOP researchers is currently in a phase 3 clinical trial and targets the pathological process that leads to excess bone growth in FOP.

CHOP researchers have discovered a heat-shock protein that requires the addition of a lipid particle to function, providing a roadmap for new antimalarial drugs.