Research News from CHOP

CHOP Researchers Show Key Differences in Emotion, Adaptation Skills of Children with Autism in School Settings
Study is largest to date to look at “real world” school conditions and how autistic children control their thoughts and emotions.
Children’s Hospital of Philadelphia Researchers Develop Tools to Measure Skeletal Muscle Function in Patients with Mitochondrial Disease
Outcome measurements revealed information about muscle weakness and differences between pediatric and adult patients.
CHOP Researchers Find Bystander CPR with Rescue Breathing Leads to Better Outcomes in Pediatric Cardiac Arrest
CHOP researchers have found that CPR with rescue breathing leads to better neurological outcomes in pediatric cardiac arrest, highlighting a need for education.
When Innovation Meets Necessity: CHOP Researchers’ Critical Contributions to the Battle Against COVID-19
Since March 2020, CHOP researchers have played a vital role in combatting the COVID-19 pandemic. Read highlights of their game-changing work.
CHOP Study Finds Children with Fontan Circulation Have Slightly Shorter Stature
CHOP researchers found that children with Fontan circulation are slightly shorter than their peers, but further studies are needed to determine whether this effect is long-lasting.
Positive Preliminary Data on CRISPR Treatment for Blood Diseases
A collaborative team of researchers, including Dr. Stephan Grupp, recently presented preliminary data showing that a CRISPR-based gene-editing therapy for inherited blood disorders is safe and effective.
CHOP Researchers: Pandemic Worsening a Global Youth Mental Health Crisis
CHOP researchers authored an editorial in JAMA Pediatrics on the effects of the COVID-19 pandemic on youth mental health.
Passing the Sniff Test: CHOP Researchers Identify SARS-CoV-2 Breath Biomarkers in Children
CHOP researchers have identified six biomarkers in the breath of children with COVID-19, laying the groundwork for a potential breathalyzer test.
CHOP Researchers Develop Coating for Endotracheal Tubes that Releases Antimicrobial Peptides
CHOP researchers have developed a coating for endotracheal tubes that prevents the growth of harmful bacteria that cause inflammation and other complications.
Children’s Hospital of Philadelphia Researchers Identify Approach for Potential Nontypeable Haemophilus Influenzae Vaccine
CHOP researchers have identified two proteins that could be used for a potential vaccine against nontypeable Haemophilus influenzae, a bacterium that can lead to death in children and adults.