Research News from CHOP
Children’s Hospital of Philadelphia Features Innovative Autism Research at the UAE’s Ministry of Health and Prevention’s Arab Health 2022 Conference
As part of a longstanding partnership with the United Arab Emirates (UAE) Emirates Health Services (EHS), Children’s Hospital of Philadelphia (CHOP)will exhibit leading medical breakthroughs in the EHS booth at the annual Arab Health Exhibition and Congress, which is taking place at the Dubai International Convention and Exhibition Centre this week.
CHOP Researchers Develop New Clinical Diagnostic Test to Identify Genetic Sources of Mitochondrial Disease
New test analyzes mitochondrial DNA to find and quantify certain variations and deletions, providing a useful diagnostic tool that helps guide treatment.
MIS-C Patients Have Deeply Dysregulated Protein Profiles, According to New CHOP Research
CHOP researchers found that levels of proteins in the plasma of patients with MIS-C are significantly dysregulated and share features with two other inflammatory syndromes.
Researchers Point to Need for Implementation Science in Pediatric Oncology
CHOP researchers have found that implementation science is underused in pediatric oncology and call for more research in this area to improve patient care.
Study Shows Climate Change Will Lead to Increase in Kidney Stones
CHOP researchers found rising temperatures due to climate change will lead to an increase in cases of kidney stones over the next seven decades.
CHOP Study Finds Infants with Low-Risk Deliveries Should Not Need Antibiotics at Birth
CHOP researchers have found infants born via uncomplicated cesarean delivery should not need antibiotics at birth to prevent early-onset sepsis.
CHOP Study Finds Poverty Affects Risk of Cleft Lip and Cleft Palate
CHOP researchers have found that indicators of lower socioeconomic status are associated with an increased risk of cleft lip with or without cleft palate.
Aberrant Splicing of CD22 in Acute Lymphoblastic Leukemia Underlies Resistance to Immunotherapy
Aberrant splicing leads to downregulation of CD22 in pediatric B-ALL, rendering malignant cells resistant to the effects of CD22-directed immunotherapies.
New Study Seeks to Preserve Kidney Function in Children with CKD
CHOP's Preserving Kidney Function in Children with Chronic Kidney Disease (PRESERVE) study was recently awarded funding from the Patient-Centered Outcomes Research Institute (PCORI). PRESERVE is a three-year, multi-institutional clinical trial evaluating blood pressure management and urine protein monitoring strategies to preserve kidney function in pediatric chronic kidney disease (CKD) patients.
CHOP Researchers Find Possible Increased Tumor Risk in Some Patients with Beckwith-Wiedemann Spectrum
Researchers have unlocked patterns to improve the diagnosis of the most common epigenetic childhood cancer disorder.