Research News from CHOP
Study Suggests Policy, Education and Training Make Youngest Novice Drivers Better Prepared for License Exam, Less Likely to Crash
New study using license data from Ohio supports reevaluating comprehensive licensing policies in all states as a strategy to reduce new driver crashes.
Structural Racism and Pandemic Stressors Associated with Postpartum Depression and Anxiety Among Black Individuals
CHOP and Penn researchers have found the combined effects of structural racism and the pandemic, known as a “syndemic,” were associated with negative postpartum mental health.
Treatment Developed by CHOP Researchers Prevents Hypoglycemia in Children with Hyperinsulinism
CHOP researchers have shown that a targeted treatment they developed is effective at controlling blood sugar in patients with hyperinsulinism.
CHOP Researchers Create Reference Model for Brain Growth over Human Lifespan
CHOP and Penn researchers, along with others, have created a new tool that benchmarks brain development over the human lifespan, based on MRI data from more than 100,000 individuals.
Opioid Prescriptions for Pediatric Patients Following Surgical Procedures Have Dropped Significantly
Study suggests larger trend of moving away from routine opioid prescriptions after surgery.
CHOP Researchers Uncover Unique Mechanism for Cancer Therapy Resistance
CHOP researchers have found that multidrug resistant tumors have reduced connections between mitochondria and endoplasmic reticulum, causing signaling dysfunction.
CHOP Researchers Redefine the Mechanisms of Dravet Syndrome
Recovery of normal signaling of a key brain cell may be a critical therapeutic target to reduce seizures and cognitive impairment.
Using Social Cues to Adjust Conversational Behavior May Be Challenging for Autistic Children and Teens
Learning to adjust talkativeness could be an important growth opportunity for verbally fluent people with autism.
CHOP Researchers Refine Experimental Prodrug Treatment of High-Risk Neuroblastoma
CHOP researchers have shown that linking a tumor-killing prodrug to a macromolecular carrier of the Poloxamer family improves retention of the drug in treatment-resistant neuroblastoma tumors.
CHOP-Led Study Finds Bortezomib Improves Survival in Children with Newly Diagnosed T-Cell Lymphoblastic Lymphoma
In a COG trial, CHOP researchers found adding bortezomib to chemotherapy significantly improved overall survival in children and young adults with newly diagnosed T-cell lymphoblastic lymphoma (T-LL).