CHOP researchers will develop gene therapies for multiple sulfatase deficiency, a devastating lysosomal storage disorder, with the goal of first-in-human trials.

CHOP researchers have shown that IgA acts as a “tuner” that regulates the number of microbes the body sees every day, restraining a systemic immune response.

While a small number of relatively low impact soccer headers did not have detrimental effects, teen soccer players should still be trained to head the ball safely

CHOP and UCLA researchers have created a tool that can discover tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets.

Children’s Hospital of Philadelphia (CHOP) announced that it has received a multi-million dollar gift from the Topolewski family, longstanding supporters of the Cardiac Center at CHOP, to establish the Topolewski Pediatric Heart Valve Center.

The disorder was identified in 21 patients with neurodevelopmental and craniofacial symptoms; causal gene may be a valuable therapeutic target.

A new study has found that, contrary to popular belief, firearm deaths in the U.S. are statistically more likely in small towns rather than big cities.

Two recent papers from CHOP cancer researchers have advanced the understanding of treatment-resistant pediatric central nervous system tumors.

Toddlers who started more intense individualized intervention had better language and social communication skills than children who started intervention later.

Study provides the first data on leadless pacemakers in a pediatric population in a real-world setting.